chelate

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Related to chelating: Chelating agent

chelate

 [ke´lāt]
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in chemotherapy of metal poisoning.

che·late

(kē'lāt),
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

(kē′lāt′)
adj. Zoology
Having chelae or resembling a chela.
n. Chemistry
A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions.
tr.v. che·lated, che·lating, che·lates
1. Chemistry To combine (a metal ion) with a chemical compound to form a ring.
2. Medicine To remove (a heavy metal, such as lead or mercury) from the bloodstream by means of a chelate, such as EDTA.

che′lat·a·ble adj.
che·la′tion n.
che′la′tor n.

che·late

(kē'lāt)
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

  1. possessing claws or pincer-like appendages.
  2. to combine with a metal ion to form a stable compound.

Chelate

A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.
Mentioned in: Nephrotoxic Injury
References in periodicals archive ?
PAR and its derivatives have been exploited extensively as chelating moieties in the synthesis of metal extracting materials by various methods including cross-linked polymerization with styrene monomers [17], physical impregnation onto various polymer substrates such as Amberlite XAD-4, XAD-1180XAD-7 and Dowex ion-exchangers [18, 19], and chemical binding onto polymers [20], silica gel [21] and nanostructured substrates [22, 23].
* Sun Care--solubilizers, dispersing agents, emollients and chelating agents
Moreover, the partial exhaustion of available chelating sites due to leaching of impregnated ligand caused irreproducible results of sorption percentages of metal ion [5].
The five tea extracts were further analyzed by investigating their chelating activity.
Since TAC is affected by metal chelating capacity, reducing power, and free radical scavenging activity of compounds (e.g., by the number of -OH groups bound to aromatic rings and conjugate diene structure of antioxidant molecules), it is obvious that each method should be applied and evaluated separately [33].
In this regard, the chelating ability of these ligands toward [Mg.sup.2+], [Ca.sup.2+], [Fe.sup.2+], [Co.sup.2+], [Ni.sup.2+], [Cu.sup.2+], [Cu.sup.+], and [Zn.sup.2+] ions usually involved in the generation of free radicals in living organisms was studied.
Among the synthetic chelating agents, it is the least toxic.
In the zinc or copper chelating assay, the chelator were able to capture the ions and inhibit the formation of [Zn.sup.2+] or [Cu.sup.2+-] murexide complex which has an absorption maximum at 462 nm where the low absorbance indicate a high chelating activity.
Chelating agents such as edetate calcium disodium (EDTA), sodium 2, 3-dimercaptopropane sulfonate (DMPS), and dimercaprol (BAL) have been reported (Table 1) [7-10].
"The expanded capacities for chelating agents at our Ludwigshafen site enable us to respond to the increasing demand in Europe."
While demand for chelating agents rises strongly in emerging countries, saturated markets in Western Europe and North America will only grow slightly over the next years.
On the other hand, Table 1 shows the reducing power and ferrous ion chelating activity of the leaf extracts of the native Rhododendron species.