chelate

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chelate

 [ke´lāt]
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in chemotherapy of metal poisoning.

che·late

(kē'lāt),
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

/che·late/ (ke´lāt)
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.

chelate

(kē′lāt′)
adj. Zoology
Having chelae or resembling a chela.
n. Chemistry
A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions.
tr.v. che·lated, che·lating, che·lates
1. Chemistry To combine (a metal ion) with a chemical compound to form a ring.
2. Medicine To remove (a heavy metal, such as lead or mercury) from the bloodstream by means of a chelate, such as EDTA.

che′lat·a·ble adj.
che·la′tion n.
che′la′tor n.

chelate

[kē′lāt]
Etymology: Gk, chele, claw
1 v, to form a bond, thus creating a ringlike complex. An example is the interaction of a metal ion and two or more polar groups of a single molecule.
2 n, (in medicine) any coordination compound composed of a central metal ion and an organic molecule with multiple bonds arranged in ring formations, used especially in chemotherapeutic treatments for metal poisoning.
3 adj, pertaining to chelation.

che·late

(kē'lāt)
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

  1. possessing claws or pincer-like appendages.
  2. to combine with a metal ion to form a stable compound.

Chelate

A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.
Mentioned in: Nephrotoxic Injury

chelate

to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning.
References in periodicals archive ?
The EDTA agricultural chelates type is projected to grow with the highest CAGR from 2015 to 2020.
Four wheat, field trials were carried out at Sakha, Gemmeiza, Sids, Mallawi, Shandaweel and Mataana research stations, as well as at Sharkia and Menia Governorates during 2001/2002 to 2008/2009 seasons to study the effect of Zn and Fe chelate and some different foliar fertilizers: Wuxal micro, Fetrilon Combi, Fetrilon and Wuxal Mn-Mg (Table 1).
Cobalt(II) chelates of mixed Schiff base derived from 2-amino-N- salicylidine-4-nitrophenol with some amino acids were prepared and investigated by using different physiochemical techniques.
Iron amino acid chelate has been proven to be one of the original models for animals to absorb Fe compound supported by studies on Fe absorption mechanism (Saltman, 1965).
These peaks are slightly shifted towards lower frequencies when the europium chelate is incorporated.
The time of harvest after chelate application is important because synthetic chelates are persistent and not biodegradable.
In the present study, we covalently linked lanthanide chelates onto the surface of preformed silica nanoparticles.
Concern over the effects of oral succimer on GI lead absorption is justified because succimer exhibits high Pb-binding affinity [Pb-DMSA chelate formation constant = 2.
Some iron chelates hold onto iron more tightly than others.
The use of lanthanide chelates for biomedical analyses is presented in Chapter 234; long lifetimes of the excited states of lanthanide ions allow the use of time-resolved spectroscopy, which leads to highly sensitive analyses devoid of background effect from the autofluorescence of the samples.
AkzoNobel, a global giant involved in the manufacturing of paints, coatings and specialty chemicals, has launched a new ingredient under its chelates business.