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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.
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References in periodicals archive ?
Influence of water temperature on behavioral interactions between juvenile brook charr, Salvelinus fontinalis and rainbow trout, Salmo gairdneri.
Do gradient and temperature affect distributions of, and interactions between, brook charr (Salvelinus fontinalis) and other resident salmonids in streams?
We monitored the traps, which caught both ascending and descending charr (larger than 10 cm), from late June (depending on ice conditions) to mid-September (depending on river closing time).
During the second week of September in 1992 and 1993, charr were caught with nylon gilinets in Froys and South Dieset Lakes (Fig.
Status of anadromous Arctic charr (Salvelinus alpinus) of the Hornaday River, Northwest Territories, as assessed through harvest-based sampling of the subsistence fishery, August-September 1990-2007.
Do northern riverine anadromous Arctic charr Salvelinus alpinus and sea trout Salmo trutta overwinter in estuarine and marine waters?
Community household surveys on the Holman subsistence Arctic charr (Salvelinus alpinus) fishery priorities, needs and traditions.
Arctic charr.--Arctic charr samples retained for energy density determination were ground whole in a blender.
My research questions are: 1) do sea-run arctic charr affect food web structure in coastal Arctic lakes; and, 2) do contaminant concentrations in traditional food fish species (e.g., lake trout and lake whitefish, Coregonus clupeaformis) differ between lakes that do and do not contain sea-run arctic charr, and can this difference be attributed to differences in food web structure?
Arctic charr is the only fish species found in Lake Hazen, located in Quttinirpaaq National Park at the northern end of Ellesmere Island in the Canadian High Arctic.
Arctic charr exhibit a wide range of phenotypic diversity throughout their geographic range.