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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.


arctic and subarctic species of the fish genus salvelinus.
References in periodicals archive ?
An Asian expatriate who usually has her dinner in some of the eateries and restaurants in the city observed that in many cases the grilled meats they serve are charred.
The course of research was as follows: any dirt was brushed off from the sample of charred wood and up to 5 mm of the top char layer was scraped with a knife from different points of the sample.
Variability of section modulus of charred cross-sections and variability of density is remarkable.
Congress passed a law in 1964 that defined and still protects bourbon's integrity: It must contain no less than 51 percent corn mash (although that mash can contain malted barley, rye and wheat, as well); must be distilled at no more than 160 proof; cannot be placed into a barrel higher than 125 proof; and must be aged for a minimum of two years in a charred, new white oak barrel.
During the activation process, they used steam to bombard the charred litter material to induce porosity.
The discovery of a charred fossilized particle of fecal matter--probably left by a millipede--that was chock-full of plant spores hints that the ancient fire burned living vegetation as well as the fuel left on the ground from previous growing seasons.
But our tree, with its feet in the creek in the bottom of Bear Canyon, was unhamed, its bark not even charred.
Above, a long-abandoned home site stands in contrast to charred remains of wildlife.
Living Memorial" includes three key elements: a charred wood cantilevered section that extends out from the Grove's northern slope; symbolic burnt trees, black carbon fiber rods with mirrored tips, which rise to street level, and a charred ground surface within the dell that allows for new vegetation to heal the area over time.
color) The original Simi Valley sign was charred in the Topanga Fire, which blackened more than 24,000 acres.
The earliest direct evidence of fire use, in the form of charred animal bones dating to between 1 million and 1.