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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Indian troops destroyed houses by using the same substance in Bahmnoo area of Pulwama on July 3, 2017, leaving a charred body of a youth in the debris.
The post Charred body found in burning car appeared first on Cyprus Mail .
A cross-section of Doha residents told Gulf Times that there is a need to raise public awareness on the risks of consuming charred food.
In addition, pure PP leaves only 0.2% charred residues at this temperature of 700[degrees]C.
Pyrolytic gas typically flames up as soon as it rises up to the surface of charred wood.
Variability of section modulus of charred cross-sections and variability of density is remarkable.
Congress passed a law in 1964 that defined and still protects bourbon's integrity: It must contain no less than 51 percent corn mash (although that mash can contain malted barley, rye and wheat, as well); must be distilled at no more than 160 proof; cannot be placed into a barrel higher than 125 proof; and must be aged for a minimum of two years in a charred, new white oak barrel.
During the activation process, they used steam to bombard the charred litter material to induce porosity.
The discovery of a charred fossilized particle of fecal matter--probably left by a millipede--that was chock-full of plant spores hints that the ancient fire burned living vegetation as well as the fuel left on the ground from previous growing seasons.
These fires destroyed the mountain village of Summerhaven and later provided the charred background for President Bush's nationally televised speech calling for action to prevent such future disasters.