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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.


arctic and subarctic species of the fish genus salvelinus.
References in periodicals archive ?
The NRW's Walter Hanks said: "We successfully released the Arctic charr in two batches of 7,000 into Llyn Padarn.
All told, the results of this study should prove important when updating the Paulatuk Charr Management Plan, which is now more than 15 years old.
DAVID HAYE has pulled out of his heavyweight bout with Manuel Charr next month after suffering a hand injury in training.
LONDON -- Controversial boxer David Haye will take on German Manuel Charr in his comeback fight on June 29, the Briton announced on Sunday.
He was a veteran of WWII, serving in the Submarine Corps aboard the USS Besugo and the USS Charr.
He had hinted that his September 8 defeat of Manuel Charr could be his last pro fight before focusing on his fledgling career in politics.
Meanwhile, Vitali Klitschko finished Manuel Charr in four rounds, while Andre Ward TKOd Chad Dawson in ten.
Klitschko, speaking in Moscow to publicise his clash with Manuel Charr on September 8, insisted Haye should have been his next opponent.
The sad part is that this problem has been known to the authorities for over 20 years, and all have chosen to bury their heads in the sands of time, whilst in the real world the fishing has completely collapsed, not only the lake but the River Seiont as well, the charr which have been with us since the retreat of the glaciers are on the verge of extinction closely followed by the brown trout, the once prolific sewin are but a distant memory, the salmon only run the system during the winter months.
2008), brown trout (Kocaman, 2009; Demir, 2010), Atlantic salmon (Hansen and Moller 1985; Peterson 1995), rainbow trout (Hodson and Blunt, 1986; Bascinar, 2010), brook trout (Kocaman, 2009; Bascinar, 2003), and Arctic charr and their hybrids (Dumas et al.
In addition, Miglavs and Jobling (1989) showed that the relative sizes of liver and viscera decreased with either feed deprivation for 16 weeks or restricted feeding, which was 10% of feed consumption at satiation feeding for 8 weeks in Arctic charr (Salvelinus aplinus) and increased to levels exceeding those of fish fed continuously to satiation after fish were transferred from restricted to satiation feeding for the following 8 weeks.