chaperones


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chaperones

Chaperonins, intracellular proteins that assist in the correct folding of other proteins by means of hydrophobic surfaces that recognize and bind to exposed hydrophobic surfaces on misfolded proteins. Chaperones also assist proteins to arrive at the sites in the cell where they carries out their function. Intracellular proteins with abnormal configurations interact abnormally with other molecules, and many disease processes relate to misfolded proteins. Misfolding of proteins that are regulators of growth and differentiation and contribute to ageing and many diseases. It may, for instance, may be an important factor in the causation of cancers. Protein misfolding may be a factor in as many as half of all diseases. Increasing understanding of this phenomenon may lead to new and important therapies.
References in periodicals archive ?
Speaking toGlamourin 2017, she said: "We have chaperones who keep an eye on us all day and then all night, too.
Emergency medical information forms must be collected for all students, teachers, and chaperones on the trip.
Gain Therapeutics SA is developing a new class of compounds: non-competitive pharmacological chaperones, identified through its pioneering proprietary platform SEE-Tx.
Crucial lifeline lost JACK Reeve, aged 15, who suffers from cerebral palsy, sensorineural hearing problems, learning difficulties and asthma, has depended on a travel chaperone since he was three.
Soluble expression of huscFv by co-expression of pET22b-huscFv with chaperones plasmids
The team discovered the identity of Ryk's chaperone: a protein named Smek.
She told Glamour magazine: "We have chaperones who keep an eye on us all day and then all night, too.
Due to the number and heterogeneity of chaperone and cochaperone proteins, the nomenclature has become complex, with some chaperones receiving multiple names.
The contract provides Cantabio with access to intellectual property derived from the joint research done at Purdue University and Cantabio, further strengthening the company's intellectual property position in DJ-1 pharmaceutical chaperones, and provides further confidence in the validity of the therapeutic program for PD and neurodegenerative diseases in general.
Ray is part of a team of 25 chaperones who assist celebrity runners at the event, which takes place on September 11 this year, and enjoys his job immensely.
I examine two research questions: (a) how are different actors or chaperones enrolled in popular texts to substantiate a specific framing in the portrayal of the Internet by the Norwegian press; and (b) how is a position transformed into a bias and how is such bias constituted?