chancre


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Related to chancre: soft chancre

chancre

 [shang´ker]
1. the primary lesion of syphilis, occurring at the site of entry of the infection. Called also hard, hunterian, or true chancre.
2. a papular lesion occurring at the site of entry of infection in tuberculosis of the skin or in sporotrichosis.

A true chancre begins as a papule which breaks down into a reddish ulcer. It is generally firm and accompanied by little or no pain. Although most frequently located on the external genitalia, it may be on the lips or fingers. In women, a chancre is sometimes concealed in the internal genitalia where it may not be seen or felt. Two or three may develop simultaneously. A chancre heals of its own accord without treatment, thus leading many persons infected with syphilis to believe they are cured. They are not, and if adequate medical treatment is not begun at this early and curable stage of syphilis, the disease will progress, doing irreparable damage.
Chancre of primary syphilis. From Frazier et al., 2000.

chan·cre

(shan'ker),
The primary lesion of syphilis, which begins at the site of cutaneous or mucosal infection after an interval of 10-30 days as a papule or area of infiltration, of dull red color, hard, and insensitive; the center usually becomes eroded or breaks down into an ulcer that heals slowly after 4-6 weeks. Finding Treponema pallidum on dark-field examination is diagnostic, except in oral ulcers, in which T. microdentium is normally present.
[Fr. indirectly from L. cancer]

chancre

/chan·cre/ (shang´ker) [Fr.]
1. the primary sore of syphilis, occurring at the site of entry of the infection.
2. the primary cutaneous lesion of such diseases as sporotrichosis and tuberculosis.

hard chancre , hunterian chancre chancre (1).
chancre re´dux  chancre developing on the scar of a healed primary chancre.
soft chancre  chancroid.
true chancre  chancre (1).
tuberculous chancre  a brownish red papule which develops into an indurated nodule or plaque, representing the initial cutaneous infection of the tubercle bacillus into the skin or mucosa.

chancre

(shăng′kər)
n.
1. A dull red, hard, insensitive lesion that is the first manifestation of syphilis.
2. An ulcer located at the initial point of entry of a pathogen.

chan′crous (-krəs) adj.

chancre

[shang′kər]
Etymology: Fr, canker
1 also called venereal sore. a skin lesion, usually of primary syphilis, that begins at the infection site as a papule 10 to 30 days after exposure to the spirochete and develops into a red, bloodless, painless ulcer with a scooped-out appearance. It heals without treatment and leaves no scar. Two or more chancres may develop at the same time, usually in the genital area but sometimes on the hands, face, or other body surface. The chancre teems with Treponema pallidum spirochetes and is highly contagious.
2 a papular lesion or ulcerated area of the skin that marks the point of infection of a nonsyphilitic disease, such as tuberculosis. Compare chancroid. See also syphilis.
enlarge picture
Chancre of primary syphilis

chancre

STD The classic 1º skin lesion of syphilis, which consists of a painless 1–2 cm ulcer; the 1º chancre is highly contagious, contains zillions of spirochetes, and heals as a papule; chancres outside the vagina or on the scrotum render condoms useless in disease-preventing systems. See Kissing chancre, Syphilis.

chan·cre

(shang'kĕr)
The primary lesion of syphilis, which begins at the site of infection after an interval of 10-30 days as a papule or area of infiltration, of dull red color, hard, and insensitive; the center usually becomes eroded or breaks down into an ulcer that heals slowly after 4-6 weeks.
Synonym(s): hard chancre, hard ulcer.
[Fr. indirectly from L. cancer]

chancre

(shang'ker) [Fr. chancre, ulcer fr. L. cancer]
Enlarge picture
TYPICAL CHANCRE OF PRIMARY SYPHILIS
A hard, syphilitic primary ulcer, the first sign of syphilis, appearing approx. 2 to 3 weeks after infection. See: illustration; syphilischancrous (shang'krus), adjective

Symptoms

The ulcer begins as a painless erosion or papule that ulcerates superficially. It generally occurs alone. It has a scooped-out appearance due to level or sloping edges that are adherent, and a shining red or raw floor. The ulcer heals without leaving a scar. It may appear at almost any site including the mouth, penis, urethra, hand, toe, eyelid, conjunctiva, vagina, or cervix. Synonym: hard chancre; hunterian chancre; true chancre

CAUTION!

During the chancre stage, syphilis is highly contagious. The chancre contains many spirochetes.

hard chancre

Chancre.

hunterian chancre

Chancre.

simple chancre

Chancroid.

soft chancre

Chancroid.

true chancre

Chancre.illustration

chancre

The painless, hard-based primary sore of syphilis, which appears on the genitals within four weeks of exposure. It is a shallow ulcer with a base resembling wet wash-leather. This teems with the spirochaetes that cause the disease.

Chancre

The initial skin ulcer of primary syphilis, consisting of an open sore with a firm or hard base.
Mentioned in: Syphilis

chancre (shang·ker),

n extremely contagious symptom of primary syphilis; appears as a lesion at the site of infection, first as a papule and then turns red; is painless and bloodless; has raised edges. Heals without leaving a scar.
Enlarge picture
Chancre.

chan·cre

(shang'kĕr)
Primary lesion of syphilis. Finding Treponema pallidum on dark-field examination is diagnostic, except in oral ulcers, in which T. microdentium is normally present.
[Fr. indirectly from L. cancer]

chancre (autochthonous ulcer) (shang´kur),

n the primary lesion of syphilis, located at the site of entrance of the spirochete into the body, occurring about 3 weeks after contact. It begins as a papule and then develops into a clean-based shallow ulcer. Secondary infection may produce suppuration. Has the appearance of a buttonlike mass because of the contiguous induration and rolled border. Weeping characteristics also are present.
chancre of lip,
n the primary lesion of syphilis that often appears as an ulcerated or crusted, indurated lesion with a brownish or copper-colored weeping base when located on the lip, which contains
T. pallidum.
chancre, soft,

chancre

the 2 to 4 in, hard, hot, painful lesion which develops at the site of tsetse-fly bites when the fly is a transmitter of trypanosomiasis. In human medicine, refers to the primary lesion of syphilis.
References in periodicals archive ?
Other differences include, HIV-positive patients tend to have more than one chancre, a larger and deeper primary lesion, higher rate of asymptomatic primary syphilis, more aggressive secondary syphilis and increase rate of early neurological involvement.
5) You don't have to pull down your partner's pants, either: Treponema pallidum jumps from oral chancres to oral abrasions with acrobatic ease.
the appearance of a chancre at the site of inoculation and dissemination of the organism.
Definite diagnosis is made when the characteristic trypanosoma parasite (trypomastigote form) is observed in blood, lymph nodes, scrapings from the chancre, bone marrow, or CSF.
Perform venereal disease research laboratory (VDRL) serum test, which are reactive by day 7 of the chancre (http://www.
After inoculation, often resulting in a chancre, the trypanosomes multiply in blood and lymph, causing the first stage of HAT.
Frank Chancre, its current Chair and running in a highly contested reelection campaign, names Lila Mae to the building in an attempt to draw votes from his more liberal opponent.
The bite site, as already stated, is often very painful and develops into a chancre.
Delays in Syphilis Diagnosis Vary With Presenting Symptoms in HIV-Positive Patients Symptom Patients with delay Median delay(days from in diagnosis symptom onset) Mouth ulcers (n=13) 69% 78 Sore throat (n=25) 56% 44 Cervical lymphadenopathy 52% 56 (n=23) Chancre (n=13) 46% 73 Inguinal lymphadenopathy 46% 36 (n=13) Subjective fever (n=18) 39% 42 Generalized rash (n=70) 23% 25 Rash on palms and soles 9% 7 (n=44) Note: Based on data for 118 syphilis cases in HIV-positive patients.
Delays in Syphilis Diagnosis Vary With Presenting Symptoms in HIV-Positive Patients Patients Median delay Symptom with delay (days from in diagnosis symptom onset) Mouth ulcers (n = 13) 69% 78 Sore throat (n = 25) 56% 44 Cervical lymphadenopathy (n = 23) 52% 56 Chancre (n = 13) 46% 73 Inguinal lymphadenopathy (n = 13) 46% 36 Subjective fever (n = 18) 39% 42 Generalized rash (n = 70) 23% 25 Rash on palms and soles (n = 44) 9% 7 Note: Based on data for 118 syphilis cases in HIV-positive patients.
As the tsetse fly feeds it inoculates the new host where trypanosomes undergo a series of divisions at the bite site producing a sore called a primary chancre.
Ce fut dans cet exercice penible, qu'elle se donna un si mechant coup au sein, qu'on ne lia jamais paguerir, & devint un chancre forme dans la suite du temps.