chancre


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chancre

 [shang´ker]
1. the primary lesion of syphilis, occurring at the site of entry of the infection. Called also hard, hunterian, or true chancre.
2. a papular lesion occurring at the site of entry of infection in tuberculosis of the skin or in sporotrichosis.

A true chancre begins as a papule which breaks down into a reddish ulcer. It is generally firm and accompanied by little or no pain. Although most frequently located on the external genitalia, it may be on the lips or fingers. In women, a chancre is sometimes concealed in the internal genitalia where it may not be seen or felt. Two or three may develop simultaneously. A chancre heals of its own accord without treatment, thus leading many persons infected with syphilis to believe they are cured. They are not, and if adequate medical treatment is not begun at this early and curable stage of syphilis, the disease will progress, doing irreparable damage.
Chancre of primary syphilis. From Frazier et al., 2000.

chan·cre

(shan'ker),
The primary lesion of syphilis, which begins at the site of cutaneous or mucosal infection after an interval of 10-30 days as a papule or area of infiltration, of dull red color, hard, and insensitive; the center usually becomes eroded or breaks down into an ulcer that heals slowly after 4-6 weeks. Finding Treponema pallidum on dark-field examination is diagnostic, except in oral ulcers, in which T. microdentium is normally present.
[Fr. indirectly from L. cancer]

chancre

(shăng′kər)
n.
1. A dull red, hard, insensitive lesion that is the first manifestation of syphilis.
2. An ulcer located at the initial point of entry of a pathogen.

chan′crous (-krəs) adj.

chancre

STD The classic 1º skin lesion of syphilis, which consists of a painless 1–2 cm ulcer; the 1º chancre is highly contagious, contains zillions of spirochetes, and heals as a papule; chancres outside the vagina or on the scrotum render condoms useless in disease-preventing systems. See Kissing chancre, Syphilis.

chan·cre

(shang'kĕr)
The primary lesion of syphilis, which begins at the site of infection after an interval of 10-30 days as a papule or area of infiltration, of dull red color, hard, and insensitive; the center usually becomes eroded or breaks down into an ulcer that heals slowly after 4-6 weeks.
Synonym(s): hard chancre, hard ulcer.
[Fr. indirectly from L. cancer]

chancre

(shang'ker) [Fr. chancre, ulcer fr. L. cancer]
Enlarge picture
TYPICAL CHANCRE OF PRIMARY SYPHILIS
A hard, syphilitic primary ulcer, the first sign of syphilis, appearing approx. 2 to 3 weeks after infection. See: illustration; syphilischancrous (shang'krus), adjective

Symptoms

The ulcer begins as a painless erosion or papule that ulcerates superficially. It generally occurs alone. It has a scooped-out appearance due to level or sloping edges that are adherent, and a shining red or raw floor. The ulcer heals without leaving a scar. It may appear at almost any site including the mouth, penis, urethra, hand, toe, eyelid, conjunctiva, vagina, or cervix. Synonym: hard chancre; hunterian chancre; true chancre

CAUTION!

During the chancre stage, syphilis is highly contagious. The chancre contains many spirochetes.

hard chancre

Chancre.

hunterian chancre

Chancre.

simple chancre

Chancroid.

soft chancre

Chancroid.

true chancre

Chancre.illustration

chancre

The painless, hard-based primary sore of syphilis, which appears on the genitals within four weeks of exposure. It is a shallow ulcer with a base resembling wet wash-leather. This teems with the spirochaetes that cause the disease.

Chancre

The initial skin ulcer of primary syphilis, consisting of an open sore with a firm or hard base.
Mentioned in: Syphilis

chan·cre

(shang'kĕr)
Primary lesion of syphilis. Finding Treponema pallidum on dark-field examination is diagnostic, except in oral ulcers, in which T. microdentium is normally present.
[Fr. indirectly from L. cancer]
References in periodicals archive ?
N Classification of cutaneous Diagnostic considerations tuberculosis 1 Exogenous Tuberculosis sporotrichosis, leishmaniasis, cutaneous chancre atypical mycobacteriosis, Tuberculosis syphilis, cat scratch disease and tularemia Tuberculosis paracoccidioidomycosis, verrucosa cutis leishmaniasis, sporotrichosis, tuberculosis verrucosa and chromomycosis.
Secondary syphilis develops 6 weeks after chancre emergence and is characterized by constitutional symptoms, skin lesions, mucosal lesions and systemic involvement.
Other differences include, HIV-positive patients tend to have more than one chancre, a larger and deeper primary lesion, higher rate of asymptomatic primary syphilis, more aggressive secondary syphilis and increase rate of early neurological involvement.
A study of 689 HIV-positive men attending two big Phoenix-area HIV clinics found that provider counseling consisting of chancre photos, sexual risk assessment, and counseling on the impact of syphilis encouraged men to look for sores more often in oral and rectal areas.
Watson's vision enables her to read Fulton's work more profoundly, alert to "myriad tiny insurrections" in its pages similar to the graffiti that defaces Chancre's campaign posters; "no one notices them but they're there, near-invisible, and count for something" (18).
Differential diagnoses include pyoderma, herpetic whitlow, cowpox, pseudocowpox (milker's nodule), cat-scratch disease, anthrax, tularemia, pri-mary inoculation tuberculosis, atypical mycobacteriosis, syphilitic chancre, sporotrichosis, keratoancanthoma, and pyogenic granuloma (5).
Jean-Gilles Malliarakis (l'Action Nationaliste) conspue <<les crimes de l'Epuration>> et glorifie la Collaboration, Francois Brigneau (Minute) s'enthousiasme quant au reveil du fascisme, Duprat (representant de Defense de l'Occident) fait l'apologie de la dictature des colonels en Grece au nom du combat contre <<le chancre rouge>>, Jean-Francois Galvaire s'ecrie qu'il faut <<faire les comptes et peut etre dresser des poteaux d'execution...
The primary stage is characterized by the appearance of a painless sore, the chancre, and the secondary stage is often marked by a maculopapular rash involving the palms of the hands and the soles of the feet, mucocutaneuous lesions, and lymphadenopathy.
The Alpha Group STOCKS 66% % BONDS 33% % CASH 1% % (no chancre)
(3,4) Approximately 5-15 days post-infection, a trypanosomal chancre, caused by the accumulation of trypanosomes in the connective tissue, may form at the site of the tsetse fly bite.
The chancre characteristic of primary syphilis begins as a papule and then erodes.
Clinically, the lesions generally start as a chancre at the trauma site, and these lesions may be associated with iymphadenopathy and lymphangitis.