Chalones | definition of chalones by Medical dictionary
Also found in: Dictionary
chalones POLYPEPTIDEs or glycoproteins, released by actively-dividing cells that inhibits chromosomal reproduction (MITOSIS) in cells of the tissue in which they are formed, thus controlling a tendency to HYPERPLASIA.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive
The lipoxins were the first identified and recognized endogenous anti-inflammatory lipid mediators which can function as "braking signals" for neutrophils or chalones
in inflammation .
Thumann & Bustos-Obregon (1978) postulated that this response is mediated by the spermatogonial chalones
, an inhibitor of spermatogonial mitosis produced by spermatogenic differentiated cells.