chalone


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chalone

 [kal´ōn]
a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.

cha·lone

(kā'lōn),
Originally, a hormone (for example, enterogastrone) that inhibits rather than stimulates; now, mitotic inhibitor (often glycoproteins) elaborated by a tissue and active only on that type of tissue, regardless of species; thus, a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

/chal·one/ (kal´ōn) a group of tissue-specific water-soluble substances that are produced within a tissue and that inhibit mitosis of cells of that tissue and whose action is reversible.

chalone

(kā′lōn′, kăl′ōn′)
n.
Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.

chalone

[kā′lōn]
Etymology: Gk, chalan, to relax
any one of numerous polypeptide inhibitors that are elaborated by a tissue and function like hormones on specific target organs.

cha·lone

(kal'ōn)
Any of a number of mitotic inhibitors elaborated by a tissue and active only on that type of tissue, regardless of species; a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

one of a group of chemicals (PEPTIDES and GLYCOPROTEINS) occurring in living animal tissues which specifically inhibit MITOSIS.

chalone

a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.
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References in periodicals archive ?
Foley Family Wines is acquiring the Chalone Estate Vineyard and Gavilan brands as well as nearly 1,000 contiguous acres, with 240 acres planted to vine.
In the year to December 31, 2003, Chalone reported gross revenues of $69.
Our map does not include North Chalone Peak Trail (which takes off south from the reservoir) because it is not as floriferous as the others and because the fire lookout, with a Monterey Bay view to reward the long push uphill, is closed until fire season.
Shortly after the Chalone agreement was reached, Chadwick was enthusiastic about the fit between Diageo's existing wine brands and Chalone.
Chalone had originally accepted an offer from DBR in partnership with Constellation and the Huneeus family of Chile, but the agreement allowed Chalone to back out of the deal if a better offer was received.
Domaines Rothschild will contribute its present 46% of Chalone shares to the joint venture.
John Probst, a veteran of 15 years in the Washington State wine industry; is the new general manager of Sagelands Vineyard, announced Chalone Wine Group.
Diageo Chateau & Estate Wines produces and markets Beaulieu Vineyard, Sterling Vineyards, the wines of The Chalone Wine Group, Sterling Vintner's Collection, Solaris, Vinavera, Archetype and Blossom Hill, as well as the French wines of Barton & Guestier.
The Californians picked for the tasting were Chalone, Kendall-Jackson, Justin, Ojai and Ravenswood.
Richard Boer, Vineyard Manager, Chalone Vineyards, Calif.
Chalone Wine Group reported an increase of 3% in its nine-month sales to 461,438 cases, compared to the same period last year.