chalone


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chalone

 [kal´ōn]
a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.

cha·lone

(kā'lōn),
Originally, a hormone (for example, enterogastrone) that inhibits rather than stimulates; now, mitotic inhibitor (often glycoproteins) elaborated by a tissue and active only on that type of tissue, regardless of species; thus, a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

(kā′lōn′, kăl′ōn′)
n.
Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.

cha·lone

(kal'ōn)
Any of a number of mitotic inhibitors elaborated by a tissue and active only on that type of tissue, regardless of species; a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

one of a group of chemicals (PEPTIDES and GLYCOPROTEINS) occurring in living animal tissues which specifically inhibit MITOSIS.
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References in periodicals archive ?
Foley Family Wines is acquiring the Chalone Estate Vineyard and Gavilan brands as well as nearly 1,000 contiguous acres, with 240 acres planted to vine.
(102.) Also, the shareholders of Chalone received a "wine
Napa-based Chalone specialises in premium red and white wines and owns a string of vineyards in California and Washington state, as well as a 23.5 per cent stake of the Fourth Growth estate of Chateau Duhart-Milon in Bordeaux in partnership with Domaines Barons de Rothschild (Lafite).
As the quoted lines suggest, "Chalone" draws histories and present conjunctures into its force field, refusing the safety of rangefinders and distanced certitudes in favor of pressing encounters.
Helena (Calif.) to the Culinary Institute of America in 1993, the sale of Chalone Vineyards to Foley in 2016, and the sale of Edna Valley Vineyards to Gallo in 2011.
-FOLEY FAMILY BUYS CALIFORNIA'S CHALONE ESTATE VINEYARD
Chalone 2010 Chardonnay (Monterey County; $13) This has it all: ideally ripe apple, citrus, and green melon; a streak of minerality; and a hint of caramel.
*** (88) Chalone Monterey Pinot Noir 2006 (California).
"We're seeing consumers trade up in spirits and wine," says Jim Green, vice president, trade marketing, national accounts, at Diageo, the Norwalk, Conn.-based manufacturer of Jose Cuervo, Crown Royal, Chalone wines and a host of other brands.
(SAC605) THOMAS SELFRIDGE - CHALONE WINE GROUP LTD (CHLN).
Diageo sold Chalone Vineyards separately to Foley Family Wines.