challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
She also absolutely adores playing the challengingly non-verbal title role that Griffin has created for her in Our Zombie Mother.
This is a challengingly imaginative novel, a riveting story, and as well a timely intervention in contemporary debates over how to understand and cope with a worldwide movement of refugees and displaced persons.
Redford, for one, is working diligently to support his survivalist film, challengingly titled "All Is Lost.
Scholarly and at times very well researched -especially in revealing the context, strategy and even the tactics of police detection-this book does occasionally plod along somewhat (her detectives show little 'ascent', despite her title), but it sits interestingly, and sometimes challengingly, beside the widely-studied flood of fictional detection.
Now Kathe did raise her head and looked challengingly at Ella.
SUPPOSE you had to choose the single motion picture that dealt most seriously and challengingly with religious matters.
BEFORE This Costa Mesa yard was little more than 1,500 square feet of tired lawn and broken tiles in a challengingly arid climate.
Houston's Harvard Law School course notes show the challengingly comprehensive and analytic instruction that he received from the faculty and how through rigorous examination he was expected to probe cases and textual meaning well beyond factual matter and further into the conceptual domain.
Also on view will be source material and documents of the work's reception, promising a fresh vantage onto one of the most conceptually subtle and challengingly beautiful oeuvres in photography today.
That's challengingly small for seeing any surface and atmospheric features, but Mars will only be a little bigger (13.
Author Philip Reeve then spoke challengingly about the situation facing libraries: 'Boo to nostalgia--it's not the reason to protect libraries', which need to recognise that books are a 15th century technology and not 'the natural order of things' to many young people who find screens more exciting.
speak the Gospel more clearly, comfortingly, and challengingly for the