challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response
References in periodicals archive ?
That's challengingly small for seeing any surface and atmospheric features, but Mars will only be a little bigger (13.9") at opposition on March 3rd.
Author Philip Reeve then spoke challengingly about the situation facing libraries: 'Boo to nostalgia--it's not the reason to protect libraries', which need to recognise that books are a 15th century technology and not 'the natural order of things' to many young people who find screens more exciting.
speak the Gospel more clearly, comfortingly, and challengingly for the
He said Nato forces work non-stop 24 hours a day and has been able to effectively maintain a no-fly zone and an arms embargo has also been effectively enforced and civilian protection has been challengingly effective.
In what is a beautifully written study, Miller challengingly proposes that Whitman became a poet rather belatedly and unexpectedly (although he had theorized the poet's role in advance) when, possibly as late as the spring of 1855, he discovered, via increasingly intensive experiments with poetic prose, the omnivorous potentialities of the long line.
She argues that Kahn's baroque version of the archive can only be understood through Bergson and, more challengingly, that Bergson's connection with the Archives de la Planete is his most significant yet overlooked involvement with the medium of film.
Some of the strangest and most distinctive aspects of Christian eroticism, such as the ascetical and mystical, are ignored or dismissed by the authors, and at least one of its most challengingly complex theorists, Augustine of Hippo, is misread with remarkable consistency.
It was reassuringly familiar yet challengingly different.
Indian brain is challengingly strong and the Indian innovations will dominate the globe with a strong impact.
During a discussion on the placement of the various beings described in one science-fiction novel (including apes and robots) on a scale from the most to the least human, Zunshine writes challengingly: "Where wouldyou put the apes?" This is the book of a gifted teacher.
Authors from challengingly diverse contexts--Caribbean, Jewish, Japanese, and Korean--are examined together in a surprisingly coherent manner thanks largely to the tight thematic focus and theoretical suppleness of the book.