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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Appeal of dismissal of action challenging income taxation and Federal Reserve notes.
Criticism and the Color Line begins with Morrison's 1989 article, published here for the first time in a book collection, which establishes the theme of the text by challenging critics to speak the unspeakable in the realm of American literary criticism through the unveiling of the black presence within canonical works.
In earlier grades, the use of so-called token economies, in which students tackle challenging problems and receive performance-based points toward valued rewards, shows promise in boosting effort and creativity the Delaware psychologist contends.
Together, the United States and Japan must continue to offer both countries a constructive course of integration into the international system: challenging a rising China to rise also to its global responsibilities; encouraging India to play a role in world affairs befitting a thriving democracy of over one billion people.
As nursing homes admit more residents with Alzheimer's disease, psychiatric disorders, and other conditions often associated with challenging behaviors, staff are faced with increasing incidents of resident violence.
If we consider the novel as a narrative in prose dealing with people and their actions in a certain time and in a certain space, all of which conveys a certain vision on the part of the author; if we utilize close reading of verb tenses, adjectives, phrases in apposition, choice of nouns, point of view, and so forth to focus on even only one of the defining aspects of the genre, we can forge a host of questions enabling students to come to grips with the central issues, themes, and challenging questions that rest at the foundation of the interconnecting elements of virtually any great novelist's work.
Instead, by designing and implementing construction plans that solve the problems posed by a site's constraints, HRH has managed to turn some of the most challenging building sites into successful realities.
Being named editor of Professional School Counseling is a humbling and challenging responsibility.
This piece presents a wealth of colorful and challenging ensemble problems made accessible by the descriptive character.
"My argument challenging the Boy Scouts' policy is to say that these people came together to celebrate shared values and to work with youth," Leishman said.
No matter what type of clientele your camp serves, the children need a safe, nurturing and challenging environment to grow in.
With improved productivity becoming a benchmark for success in today's challenging economic environment, business process management (BPM) is a critical business function.