challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
The issue of whether the competent United States court applied the Act of State doctrine or not is irrelevant in the light of the concept of challengeable act for the purposes of Article 230 EC.
However, even when we neglect these facts and accept the basic CTL model (whose assumption of a decline of the growth rate by 2 percentage points far exceeds the estimates of the studies quoted by Atkinson), we are left with challengeable considerations.
9) This official assertion is challengeable both on its own terms and in relation to greater threats that loom as more than long-shot possibilities (e.
It also creates another legally challengeable decision.
However, these assumptions have become challengeable by the modified understandings of "individuals" and their minds that have arrived with the maturation of these "fragile sciences.
Sir Ian himself said: "I think the facts in Da Vinci Code may well be challengeable, but maybe the truths are not.
In other words, while any particular turn of thought may be a function of my Verstand, to the extent that it is rational, repeatable, challengeable, verifiable or refutable, it also must be a manifestation of a general Verstand or universal reason that is common to all who participate in rational, logical, and enlightened debate.
Pena says that the F-15 Eagle is not challengeable by any potential adversary.
As we see the struggles of people all over the world to live together, even those who have occupied the same country for a thousand years, we can rejoice in our ability to leverage our difference to create a new society where freedom exists, where everything is challenged and challengeable, where we can be an independent and diverse community.
Broadbent (2001) * Clear expectations * Satisfaction Black (1998) * Challengeable expectations * Clear business objective * Short classes Brown (1996) Chyung (2000, 2001a, 2001b) * Attraction * Confidence * Relevance * Satisfaction Chyung et al.
Any national or local policy of a WTO or NAFTA signatory nation that falls outside WTO or NAFTA's terms--even if it has nothing to do with trade per se--is challengeable as an "illegal trade barrier" before a WTO or NAFTA tribunal.
The process of collecting or disseminating of visual data over internet, especially those which are dealing with concepts of spatial entity like architectural content, is becoming a challengeable task.