challenge


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Idioms, Encyclopedia, Wikipedia.

challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response
References in periodicals archive ?
'We want to clear something up regarding the Momo Challenge: We've seen no recent evidence of videos promoting the Momo Challenge on YouTube.
This is not the first time a challenge on social media sparked concerns.
The company did not identify the so-called Bird Box challenge as among those that will be prohibited on the platform, but the announcement came less than a week after a teenager in Utah crashed his car while doing the said task.
He said the main purpose of conducting this Challenge was to encourage the emergency services across the country to enhance their professional skills and competencies to meet new challenges resulting from increasing number of emergencies.
Tucson, AZ, October 05, 2018 --(PR.com)-- Viral internet challenges are exploding in popularity.
According to reports, this challenge has been encouraging children to perform dangerous challenges that ultimately lead to committing suicide.
At each challenge, teams will earn points based on how fast they complete the challenge after checking in.
Who can challenge? The PSPs who wish to challenge must be legally, technically and financially capacitated.
Full details of how to enter the 2018 Young Innovators Challenge can be found at www.3M.co.uk/younginnovators
The challenge - which will start on October 20 aims to turn Dubai into the most active city in the world.
"I've got a full card on the EuroPro Tour but getting Challenge Tour status would have been extremely difficult so I'm very grateful for this opportunity.
The Ice Bucket Challenge has been promoted by the ALS Association that aims to spread awareness and funds for patients suffering from the Amytrophic Lateral Sclerosis ( ALS), also known as Lou Gehrig's disease or Motor Neuron Disease.