challenge


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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
You can follow Megan on her new Body By Vi 90 Challenge on her new blog, www.
Rehnquist's crabbed view would make it virtually impossible to challenge many government subsidies to religion.
In the event of a tie on Highest, Longest, Most challenges (for example, if two teams have a 20-stair ollie) both teams get the 50 points.
Students tell us the Dairy Challenge is one of the most valuable experiences they get outside the classroom.
In addition to describing the various challenges offered by classroom teachers, I will describe some possible resolutions to these challenges in the hope that teachers will find ways to implement a workshop approach to reading instruction during these troubling times.
Today, the heirs of Prime Minister Yoshida are rising to the new challenges of a new era.
If you use LIDB to submit a price challenge, you need to periodically return to LIDB's Price Challenge to get the source of supply response to your challenge.
At the time of the challenge you are permitted one step and an arm's reach to locate your coin.
He also said he never received any information from the election board detailing the process--which made him vulnerable to a challenge.
And, most important, he stands at the pinnacle of his career because he has thoroughly internalized a value system and code of conduct that has enabled him to overcome the challenges he's faced throughout his cadet life and his military career.
The Physical Training Unit (5) started the Challenge as part of a class for the NA.