challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
In the championship match the winner in match 2 will chalenge No.
It hath beene no custome in mee of all other men (courteous Readers) to commit my plaies to the presse: the reason, though some may attribute to my own insufficiencie, I had rather subscribe, in that to their seueare censure, then by seeking to avoide the imputation of weakenes, to incurre a greater suspition of honestie: for though some have used a double sale of their labours, first to the Stage, and after to the presse, For my owne part, I heere proclaime my selfe euer faithfull in the first, and never guiltie of the last: yet since some of my plaies have (vnknown to me, and without any of my direction) accidentally come into the Printers handes, and therefore so corrupt and mangled, (coppied onely by the eare) that I have bene as vnable to know them, as ashamde to chalenge them.
(81.) "I am Geffray with pe grete toethe sone to Raymondyn of Lusygnen that come hether to chalenge the trybute that thrughe thy pryde thou takest of my faders people" (frag, 1va), which compresses the manuscript's phrasing: "And Geffray ansuered in this manere.
However, several factors make adhesion to the root canal system a chalenge, such as chemical substances used during the biomechanical preparation, volumetric changes that occur in resin-based sealers during polymerization, bonding of the sealer because of polymerization shrinkage stresses, and various geometric factors.
ANO Tema/Titulo Tema 1: Educacao em enfermagem e o campo da saude do trabalhador 1950 Ideological barriers to teaching by health workers 1966 Occupational health nursing for the basic nursing student 1967 An occupational health nursing study 1974 Nursing education and the occupational health setting 1976 An experiment in occupational health nursing teachin 1979 Occupational health nursing - a new chalenge to educational institutes 1980 Occupational health nursing in space age society ...
It is a big chalenge. Agents say, wait, we'll just go after the big affluent market.
89-105 in The Internet and Surveillance: The Chalenge of Web 2.0 and Social Media, edited by C.
If "the affluent society" is to avoid ending up as a "nanny state" with" over grown babies" that are only capable of opening their mouths, art must chalenge and force the public out into an active situation, emphasises Lembourn, who during the 1971-81 period was chairman of the Danish Authors' Society (Lembourn 6).
Para muitos autores e consensual a analise do turismo esportivo como uma inter-relacao entre as areas e nao uma ruptura entre o esporte e o turismo, entre estes autores se destacam Standeven e De Knop com a obra "Sport Tourism" (1999), Pigeassou, Bui-Xuan e Gleyse com "Epistemological Issues on Sport Tourism: Chalenge For a New Scientific Field" (2003), Gammon e Robinson em "Sport and Tourism: A Conceptual Framework" (2003), Kurtzman e Zauhar com "A Wave in Time--The Sports Tourism Phenomena" (2003), entre outros.
Division One leaders Newdigate trounced Bermuda 8-0 with doubles by Carl Foster and John Russell but a single goal from Steve Molloy was sufficient to sustain Chetwynd Reserves' 100-per-cent Division Two record despite a stiff chalenge from Bedworth Conservatives.
Purulent pericarditis: A continuing surgical chalenge. J Nat Med Assoc 1981;73(5):439-443.