Also found in: Wikipedia.


The parent compound of a series of plant pigments. All are flavonoids and typically colored yellow to orange.
Synonym(s): benzalacetophenone
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
In second stage of first phase, docking studies of chalcone derivatives including bavachalcone (3), bavachromene (4), isobavachalcone (5) and neobavachalcone (6) were performed because of the structural homology.
* Gan X, Hu D, Chen Z, Wang Y, Song B (2017) Synthesis and antiviral evaluation of novel 1,3,4-oxadiazole/thiadiazole chalcone conjugates.
The internship was part of her thesis research project on 'Design and synthesis of novel chalcone analogs as a potential treatment for triple negative breast cancer' under the supervision of Dr Ashraf Khalil, Dr Feras Alali and Dr Ala-Eddin Almustafa.
The compounds derived from the chalcone nucleus, which incorporate electron-donating substituents in benzene rings, have interesting biological activity as antioxidants, anticancer, antifungal and antituberculosis (Liu, Wilairat, Croft, Tan, & Go, 2003; Satyanarayana, Tiwari, Tripathi, Srivastava, & Pratap, 2004).
[15] As demonstrated by Lin et al., [16] some subgroups of flavonoids have been shown to have high inhibitory activity on xanthine oxidase such as chalcone flavonoids, planar flavones, and flavonols bearing a 7-hydroxyl group.
The [sup.1]H NMR spectra of the compounds were done by dissolving the compounds in CD[Cl.sub.3] and two diagnostic doublets in the spectrum around [delta] 6.7-74 and [delta] 7.3-78 ppm for -CO-CH= ([alpha]-H) and =CH-Ar ([beta]-H), respectively, with coupling constant (J = 17 HZ) confirmed the formation and trans (E) arrangement of the chalcone bridge.
Suwito, Jumina, Mustofa et al., "Design and synthesis of chalcone derivatives as inhibitors of the ferredoxin - Ferredoxin-NADP+ reductase interaction of Plasmodium falciparum: Pursuing new antimalarial agents," Molecules, vol.
Chalcone, a well-known p53-MDM2 inhibitor, binds to the p53 pocket on MDM2 to inhibit the p53-MDM2 interaction at a micromolar range concentration [46].
Robinson et al., "Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols," Nature Biotechnology, vol.
Among these genes, five have alternative transcripts/multigene members including two phenylalanine ammonia-lyases (PAL), six 4-coumarate:CoA ligases (4CL), three chalcone synthases (CHS), two flavonol synthases (FLS), and two dihydroflavonol 4-reductases (DFR).
Thermal degradation of TAC includes the chalcone formation or loss of glycosyl moieties [26].
Herein, we report on the isolation of kojic acid from sago waste and utilized it as a precursor for the synthesis of kojic acid ester bearing chalcone 3a-c and azobenzene 5a-d moieties.