Enfeksiyon bolgesinde Chagoma
denilen, vektor bocegin soktugu yerde olusan sert ve eritematoz bir lezyon olusmaktadir.
(10) Romana's sign, a swelling around the eye where the bug has bitten or a swelling elsewhere on the body termed a chagoma
, are indications that an individual may have been exposed and should be tested for presence of the organisms.
During the acute stage, infected individuals may develop unspecific symptoms such as fever, nausea, diarrhea, and rash, as well as severe symptoms such as a raised inflammatory lesion at the site of parasite entry (chagoma
), unilateral periorbital edema (Romana's sign), lymphadenopathy, and hepatosplenomegaly .
The acute stage starts shortly after infection in which a localized skin nodule called a chagoma
appears at the inoculation site.
Approximately 50% of symptomatic Chagas patients develop a chagoma
, which can be described as a nodule or furuncle at the site of the bite (Roberts & Kemp, 2001).