cervical ripening


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cervical ripening

The stromal response of the cervix in phase 1 of parturition, which precedes the onset of labour, in which the cervix becomes softer and more dilatable.

cervical ripening

Obstetrics The stromal response of the cervix in phase 1 of parturition, which precedes the onset of labor, in which the cervix becomes softer and more dilatable. See Cervical effacement.

cervical ripening

The biochemical changes in the cervix that take place gradually over the last few weeks of gestation in preparation for childbirth. The cervix softens, and its potential for stretching increases. Normally this occurs naturally, but in postterm pregnancies it may be necessary to use mechanical dilators or drugs. Placement of Laminaria digitata or prostaglandin E analogs (e.g., misoprostol) in the vagina or cervical canal promotes cervical ripening and onset of labor but does not reduce the rate of cesarean deliveries.

Patient care

Fetal status is assessed by monitoring the heart rate for 30 min before gel insertion and for approx. 1 hr after the procedure. The woman is assessed for uterine contractions and signs of hyperstimulation, nausea, or vomiting. If hyperstimulation occurs, the gel is removed, and the primary health care provider is notified.

References in periodicals archive ?
Sublingual Misoprostol for cervical ripening before diagnostic hysteroscopy: a randomized and prospective study about 108 cases].
Sublingual misoprostol for preabortion cervical ripening in first-trimester pregnancy termination.
Table 2 summarizes labor and delivery events and outcomes among spontaneous deliveries/ no interventions, augmented spontaneous labor by artificial rupture of membranes (AROM), augmented spontaneous labor utilizing oxytocin, induced labor using cervical ripening agents and/or oxytocin, and scheduled cesarean deliveries.
The Cook Cervical Ripening Balloon catheter is comprised of two silicone balloons and uniquely engineered to allow the cervix to naturally and gradually dilate prior to the induction of labor.
In these women, induction with prostaglandins is associated with uterine rupture, they noted, explaining that prostaglandins affect both cervical ripening and contractions simultaneously, whereas the ideal strategy for induction is likely administration of a cervical ripening agent before stimulation of contractions.
In contrast, elective inductions without cervical ripening in multiparous women were not associated with an increased rate of cesarean section.
When asked if the study was mixing cervical ripening with labor induction, Dr.
Ardana has two products in clinical development and a number of pre clinical compounds including those which address male contraception, female sexual dysfunction and cervical ripening.
Misoprostol should not be used for cervical ripening or labor induction in patients who have had a cesarean delivery or major uterine surgery.
The randomized, double-blind, multi-center study tested three doses of the MVI in 374 women undergoing cervical ripening and induction of labor at 11 sites across the U.
Searle has become aware of some instances where Cytotec, outside of its approved indication, was used as a cervical ripening agent prior to termination of pregnancy, or for induction of labor, in spite of the specific contraindications to its use during pregnancy.