International periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome cohort: description of distinct phenotypes in 301 patients.
Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults.
Accompanying signs and symptoms included aphthous stomatitis (38%), pharyngitis (85%), and cervical adenitis (62%).
Herlin, "Periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis," Danish Medical Journal, vol.
Kone-Paut, "Is colchicine an effective treatment in periodic fever, aphtous stomatitis, pharyngitis, cervical adenitis
(PFAPA) syndrome?" Joint Bone Spine, vol.
C-reactive protein in the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis
EPTB was diagnosed in 2.3% of the HIV positive patients, the commonest being cervical adenitis
(1.9%) of the cases followed by pleural effusion (0.4%) of the cases.
Diagnostic problems of tuberculous cervical adenitis
-- Only scanty evidence exists to guide the treatment of the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis
, said Dr.
The syndrome--known as PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis
)--is marked by the following features:
and scarlatiniform rash are less common, he noted.
The symptoms that most significantly correlate with a positive strep result are tonsillar exudate, scarlatina rash, and anterior cervical adenitis
, according to a recent study by Dr: Todd and his colleagues (Pediatrics [online] 11116], 2003; www.pediatrics.org/cgi/content/full/111/6/e666).