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A waxlike, golden, or yellow-brown pigment first found in fibrotic livers of choline-deficient rats, and also known to be present in some cirrhotic livers (and certain other tissues) of human beings. Ceroid is acid fast, insoluble in fat solvents, and probably a type of lipofuscin although differing from true lipofuscins by failing to stain with Schmorl ferric-ferricyanide reduction stain; it also exhibits autofluorescence. Accumulates in Hermansky-Pudlak syndrome.
[L. cera, wax, + G. eidos, appearance]
Farlex Partner Medical Dictionary © Farlex 2012
ceroidA complex of alcohol-insoluble, oxidised polyunsaturated lipid pigment(s) resulting from the peroxidation of unsaturated lipids, which are similar or identical to lipofuscin. Ceroid accumulates in macrophages of the heart, liver, gastrointestinal tract and brain in the elderly, and is thus termed a “wear and tear” pigment; it has been inculpated in age-related organ dysfunction hypovitaminosis E, cathartic colon, and hereditary conditions (e.g., Batten’s disease and sea-blue histiocytosis).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
ceroidA complex of alcohol-insoluble, oxidized polyunsaturated lipid pigment(s) resulting from the peroxidation of unsaturated lipids that are similar or identical to lipofuscin; ceroid accumulates in macrophages of the heart, liver, GI tract, and brain in the elderly and is thus termed 'wear and tear' pigment; it has been inculpated in age-related organ dysfunction–see 'garbage can' hypothesis, hypovitaminosis E, cathartic colon, and hereditary conditions–eg, Batten's disease, sea-blue histiocytosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.