cerebral malaria


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ce·re·bral ma·lar·i·a

a form of falciparum malaria characterized by cerebral involvement, with extreme hyperthermia and headache, and a case fatality rate of about 50%.
Farlex Partner Medical Dictionary © Farlex 2012

cerebral malaria

Falciparum malaria in which the brain is affected. This fulminant disease often produces coma, shock, or sudden death.
See also: malaria
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
* In a study by Kochar et al, [12] anaemia were most common manifestations followed by DIC and cerebral malaria. This shows that the spectrum of common manifestations and complications of malaria vary in different geographical regions depending upon parasitic factor, epidemiological factors and host defence factors.
'Children under the age of six years, pregnant women and people who are not indigenous to areas where malaria is pervasive and have not yet fostered this immunity by building up enough antibodies, are left susceptible to the more severe manifestations of cerebral malaria,' Dr Shabani says.
In our model of cerebral malaria, cytokine mRNA expression patterns in the brain were influenced by sex; thus, therapeutic manipulation of the immune system may affect brain function.
Seydel et al., "Activated neutrophils are associated with pediatric cerebral malaria vasculopathy in Malawian children," MBio, vol.
Among malaria patients with blood group O, the prevalence of haemolytic-uremic syndrome and cerebral malaria was 13.16% and 5.25%, respectively, which was lower than that of the other three blood types.
The other most severe complication of malaria is cerebral malaria, marked by impaired consciousness, coma, neurologic abnormalities and seizures [45,47,50,51].
falciparum human malaria, where infected mice exhibit a marked systemic inflammatory response, profound thrombocytopenia, and cerebral malaria (12).
Hypoglycaemia was associated with mortality in multisystemic infections, cerebral malaria, bronchopneumonia and malignancies (Table 5).
In total, 50 per cent of patients with vivax infection had one or more complications, with severe anaemia in 26 per cent and cerebral malaria in 12.5 per cent.
Because his clinical condition worsened rapidly, the patient was transferred the next day to the Infectious Diseases Department in the same hospital because cerebral malaria was diagnosed.
falciparum complicated by cerebral malaria. The remainder were discharged.
Washington, May 7 (ANI): A new research has shown that a known drug can prevent brain damage in a cerebral malaria mouse model and eliminate subsequent neurological deficits.