A cerebellum-specific hexadecapeptide localized in the perikarya and dendrites of cerebellar Purkinje cells; used as a marker for Purkinje cell maturation studies of neural development.
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For example, incorporation of SS#2 in the L2 domain of neurexin 1a decreases its binding to [alpha]-dystroglycan, while SS#4 regulates the affinity of neurexins to postsynaptic partners such as neuroligins, LRRTMs, [alpha]-dystroglycan, cerebellin precursor protein, and latrophilin/ADGRL (recently reviewed by [23, 68, 75]).
Malendowicz, "Cerebellin in the rat adrenal gland: gene expression and effects of CER and [des-[Ser.sup.1]]CER on the secretion and growth of cultured adrenocortical cells," International Journal of Molecular Medicine, vol.
In addition, recently, four additional receptors have been identified which include Down syndrome cell adhesion molecule (DSCAM) [66], integrin [alpha]3[beta]1 and [alpha]6[beta]3 [67, 68], cerebellin 4 (CBLN4) [69] (Figure 2), and a controversial receptor adenosine receptor (A2bR) [70].