References in periodicals archive ?
Wallerian degeneration of the bilateral middle cerebellar peduncles. J Neurol Sci 2015;349:256-7.
Bilateral Wallerian degeneration of the middle cerebellar peduncles due to paramedian pontine infarction: MRI findings.
First patient with weakness of both legs, had hyperintensities in subcortical and periventricular white matter, internal capsule, pons and cerebellar peduncle. Second patient having right hemiparesis, had altered signal intensity at the cortical and subcortical areas of left frontal and parietal lobeplus significant atrophy of left cerebral hemisphere.
Cut sections through the brainstem and cerebellum disclosed the neoplasm that infiltrated the entire pons, extended into the midbrain, medulla, cerebellar peduncles, and caudal diencephalon (Figure 3).
Caption: Figure 3: Cut sections through the brainstem and cerebellum showingthe neoplasm infiltrating the entire pons, extending into the midbrain, medulla, cerebellar peduncles, and caudal diencephalon.
Pattern 7 atrophy (Cerebellar Peduncles) is seen in 1 case of atypical Parkinson's disease.
Signal changes in cerebellar peduncles (Pattern 5) are seen in 2 cases of Wilson's disease, 1 case of ataxia and atypical Parkinson's disease.
(1) Toxic exposure from heroin-induced leukoencephalopathy often involves bilateral symmetric damage to cerebellar white matter, posterior cerebral white matter; typically occipital lobe, posterior limb of internal capsule and cerebellar peduncles. (2)
Most of the parenchymal lesions are found in the infratentorial region (brain stem, cerebellum, and middle cerebellar peduncles) which were not present in our case [13].
There is severe hypogenesis of the cerebellar vermis, enlarged, horizontal superior cerebellar peduncles, a small mid brain in the anteroposterior direction, and a "batwing" configuration of the mid-superior fourth ventricle (Figures 1 and 2).
Dysgenesis of the pontomesencephalic isthmus results in the molar tooth appearance with widening of the interpeduncular cistern and abnormal thickening of the elevated superior cerebellar peduncles. This case demonstrates the clinical and imaging findings of this rare disorder.
Similar lesions may also be found in the middle cerebellar peduncles and in the hemispheric white matter involving the centrum semi ovale and extending, in some cases, into the adjacent white matter.