ceramide


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ceramide

 [ser´ah-mīd]
the basic unit of the sphingolipids, consisting of sphingosine or a related base attached via its amino group to a long-chain fatty acid anion. Ceramides accumulate abnormally in farber's disease.
ceramide glucoside the major sphingolipid accumulated in Gaucher's disease.
ceramide lactosidosis a sphingolipidosis in which ceramide lactoside accumulates in neural and visceral tissues owing to a deficiency of a β-galactosidase.
ceramide trihexoside the major sphingolipid accumulated in Fabry's disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cer·a·mide

(ser'ă-mīd),
Generic term for a class of sphingolipid, N-acyl (fatty acid) derivatives of a long chain base or sphingoid such as sphinganine or sphingosine; for example, CH3(CH2)12CH=CH-CHOH-CH(CH2OH)-NH-CO-R, where R is the fatty-acyl residue, attached in this example to 4-sphingenine (sphingosine) in amide linkage. Ceramides accumulate in people with Farber disease.
Farlex Partner Medical Dictionary © Farlex 2012

ceramide

(sîr′ə-mĭd′, sĕr′-)
n.
Any of a group of lipids that are formed by the linking of a fatty acid to sphingosine, are found in cell membranes, and help to regulate the differentiation, proliferation, and death of cells.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cer·a·mide

(ser'ă-mīd)
Generic term for a class of sphingolipid, N-acyl (fatty acid) derivatives of a long chain base or sphingoid such as sphingenine or sphingosine. Ceramides accumulate in people with disseminated lipogranulomatosis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Other indirect mechanisms linking ceramide and mitochondria include ceramide's interaction with protein kinase PKC and mitogen-activated protein kinase (MAPK).
Modulation of a ceramide pathway has revealed the sensibility of cancer cells to antineoplastic agents.
It is therefore likely that the presence of fatty liver will become inconsistent particularly in some of the subjects in the groups categorized as "obesity" and "obesity + HS." Regardless, the association found among the subspecies of ceramides and hepatic steatosis markers are independent of this stratification and it might even be more likely that a better delimitation of hepatic steatosis in the study subjects could enhance diagnostic attributes of C14:0 ceramide to predict the disease.
It is also reported that in the diabetic model animals, myocardial ceramide content was significantly increased accompanied with cardiac dysfunction [33, 34].
Researchers found that MS patients with high body mass indexes (BMIs) had higher ceramide levels and more circulating monocytes than were evident in healthy individuals with the same BMIs.
Without ceramide replenishment, the skin moisture barrier becomes greatly compromised.
Ceramedx products contain an exclusive Riceramide-3 Complex, a plant-based ceramide technology that helps heal dryness, improve moisture retention and prevent flaking and irritation from recurring.
The dihydroSph is N-acetylated by ceramide synthases (CerS) that exists in 6 isoforms (CerS1 to CerS6), which add fatty acyl chains of defined chain length to dihydroSph to generate dihydroCer.
There are only a few reports about Chinese infants [6, 13], and there is much less information about SC components, especially ceramide and protein secondary structure, which are important for SC functionality.
The formula has a proprietary ceramide complex, which helps replenish the skin's natural moisture barrier so it can maintain optimal hydration.