cephapirin/ceph·a·pi·rin/ (sef″ah-pi´rin) a semisynthetic analogue of the natural antibiotic cephalosporin C, effective against a wide range of gram-negative and gram-positive bacteria; used as the sodium salt.
a parenteral first-generation cephalosporin antibiotic.
indications It is prescribed in the treatment of bacterial infections caused by cephapirin-susceptible strains of a wide variety of microorganisms that cause septicemia, endocarditis, osteomyelitis, and bacterial infections of the respiratory tract, urinary tract, and skin.
contraindication Known sensitivity to cephalosporin antibiotics prohibits its use.
adverse effects Among the most serious adverse reactions are neutropenia, leukopenia, anemia, bone marrow depression, and allergic reactions.
a first generation cephalosporin antibiotic, resistant to β-lactamase. Most commonly used as an intramammary infusion in cows.