cephalothin


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cephalothin

 [sef´ah-lo-thin]
a semisynthetic first-generation cephalosporinantibiotic, effective against a wide range of gram-positive and a limited range of gram-negative bacteria.

cephalothin

Cefalotin® Infectious disease A parenteral semisynthetic derivative of cephalosporin C, and 3rd generation broad-spectrum cephalosporin
References in periodicals archive ?
With the aid of sterile forceps, cephalothin and nalidixic acid discs were placed on the surface of inoculated plate and incubated at 37[degrees]C for 3-6 days under microaerophilic conditions.
coli, 13% of the isolated strains have shown resistance to the antibiotics amoxicillin with clavulanate, ampicillin, cephalothin, cefepime, cefoxitin, ceftazidime, cefuroxime and meropenem.
The following antibiotics were used for bacteria isolated from urine cultures; amikacin (30ug), (20ug of amoxicillin + 10ug of clavulanate), cefotaxime (30ug), cephalothin (30ug), gentamycin (10ug), nalidixic acid (30ug), nitrofurantion (300ug), norfloxacin (10ug), sulfamethoxazole (100ug) and vancomycin (30ug) (Bioanalyse, Turkey).
Extremely high resistance rates to ampicillin, cephalothin, cefuroxime, amoxicillin-clavulante, and nitrofurantoin (91.1%-99.0%) were observed.
Antibiotics used in these studies were amikacin (Ak) amoxicillin (Am) ampicillin (A) carbenicillin (Ca) cefixime (Cfm) ceftizoxime (Cxm) ceftriaxone (Cz) cephalothin (Cl) chloramphenicol (C) ciprofloxacin (Cip) co-trimoxazole (Co) enoxacin (E) erythromycin (Er) gentamicin (G) kanamycin (K) nalidixic acid (Na) penicillin (P) streptomycin (S) sulfamethoxazole-trimethoprim (SxT) and tetracycline (T).
The antibiotic tested included: ampicillin (10 [micro]g), augmentin (30 [micro]g), cloxacillin (30 [micro]g), cephalothin (30 [micro]g), ciprofloxacin (5 [micro]g), chloramphenicol (30 [micro]g), trimethoprim (5 [micro]g), gentamicin (10 [micro]g), tetracycline (30 [micro]g), ofloxacin (5 [micro]g), and erythromycin (30 [micro]g) (Remel, USA).
It has been reported susceptible to amikacin, imipenem, cefoxitin, clarithromycin, ciprofloxacin, and cephalothin. It has variable susceptibility to doxycycline.
Klebsiella spp., the second common germ producing UTI, showed the highest sensitivity to Ciprofloxacin (81.3%) and Amikacin (73.1%) and the highest resistance to Ampicillin (86.3%) and Cephalothin (62.4%).
The following antibiotic discs (Mast Diagnostics, UK) at the final concentrations that are indicated were used: ampicillin (AP) -10 [micro]g, cephalothin (KF) 5 [micro]g, streptomycin (S) 10 [micro]g, erythromycin (E) 15 [micro]g, chloramphenicol (C) 30 [micro]g, neomycin (NE) 30 [micro]g, amoxycillin (A) 10 [micro]g, ciprofloxacin (CIP) 5 [micro]g, trimethoprim (TM) 25 [micro]g, kanamycin (K) 30 [micro]g, and oxytetracycline (OT) 30 pg.
The disks contained the following antibiotics: 10 [micro]g ampicillin, 30 [micro]g cephalothin, 30 [micro]g cefotaxime, 30 ug ceftazidime, 30 [micro]g cefuroxime, 1 [micro]g dicloxacillin, 15 [micro]g erythromycin, 10 [micro]g gentamicin, 5 [micro]g pefloxacin, 10 IU penicillin, 30 [micro]g tetracycline, and 25 [micro]g trimethoprimsulfamethoxazole.