cephaloridine


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Related to cephaloridine: cephalothin, cephalexin

cephaloridine

(sĕf″ă-lor′ĭ-dēn)
An analogue of the antibiotic cephalosporin C.
References in periodicals archive ?
Ampicillin 10 pg 7 35 R Cephaloridine 30 pg 8 40 R Chloramphenicol 30 pg 6 30 R Clindomycin 2 pg 18 90 S Doxycillin HCl 30 pg 5 25 R Erythromycin 15 pg 5 25 R Gentamicin 10 Pg 6 30 R Lincomycin 15 pg 16 80 S Nalidix acid 30 pg 5 25 R Oxytetracycline 30 pg 2 10 R Pencillin G 10 i.u 18 90 S Streptomycin 10 pg 5 25 R Tylosin 16 pg 15 75 S No.
The strain DM15 showed sensitivity towards erythromycin, bacitracin, penicillin, chloramphenicol, tetracycline, carbenicillin, cephaloridine and novobiocin.
When patients with a positive history of penicillin-allergy received first-generation cephalosporins, which share a chemical side chain similar to penicillin or amoxicillin (cephalothin, cephaloridine, cephalexin, cefadroxil, and cefazolin, plus the early second-generation cephalosporin, cefamandole), they exhibited a significant increased risk of an allergic reaction to the cephalosporin.
(50) For example, among 19 well-characterized patients allergic to penicillin who were studied for their sensitivity to the cephalosporins, cephaloridine and cefamandole (which have identical or very similar side chains to penicillin and were therefore potentially cross-reactive) only 2 (10.5%) reacted to cefamandole, while the other 17 patients tolerated both agents.
According to the manufacturer's instructions, the colonies were spread on two indicator disks, containing benzylpenicillin and cephaloridine with clavulanic acid, respectively.
Apparently, the time needed to achieve peak concentration ([T.sub.max]) for drugs administered by the intramuscular route is comparable for infants, children, and adults for aminoglycosides, ampicillin, and carbenicillin [11-14], whereas preterm infants exhibit delayed absorption of chloramphenicol, rifampicin, cephalexin, cephaloridine, and benzylpenicillin [10,11,15,16].
The organisms isolated were subjected to antibiotic susceptibility test using the following antibiotics: amikacin, gentamycin, ciprofloxacin, cefotaxime, chloramphenicol, tetracycline, erythromycin, ampicillin, cloxacillin, cefuroxime, cephaloridine, co-trimoxazole, imipenam, carbenecillin, piperacillin, polymyxin & amoxycillin.
This bacterium is consistently resistant to penicillins and classic cephalosporins (e.g., cephalothin and cephaloridine), but not to carbapenems.