centrosome


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centrosome

 [sen´tro-sōm]
a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.

cy·to·cen·trum

(sī'tō-sen'trŭm),
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
[cyto- + G. kentron, center]

centrosome

/cen·tro·some/ (sen´tro-sōm) a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.

centrosome

(sĕn′trə-sōm′)
n.
A small region of cytoplasm adjacent to the nucleus that contains the centrioles and serves to organize microtubules.

cen′tro·so′mic (-sō′mĭk) adj.

centrosome

Etymology: Gk, kentron + soma, body
a self-propagating cytoplasmic organelle present in animal cells and in those of some lower plants. The structure, which consists of the centrosphere and the centrioles, is located near the nucleus of the cell center or attraction sphere and functions as the dynamic center of the cell, especially during mitosis. Also called cytocentrum, microcentrum, paranuclear body.

centrosome

(1) Uncertain; possibly the microtubule organising centre (MTOC). 
(2) The smallest hypothetical unit of life, the cytocentrum.

cy·to·cen·trum

(sī'tō-sen'trŭm)
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
Synonym(s): centrosome, microcentrum.
[cyto- + G. kentron, center]

centrosome

A small mass of CYTOPLASM, lying near the nucleus of a cell and consisting of a pair of centrioles, which divides into two parts before cell division. These migrate to the poles of the cell and the spindle develops between them.

centrosome

an area of cell CYTOPLASM found near the nucleus, whose function is thought to be the organization of nuclear division since it is capable of assembling and disassembling MICROTUBULES. When nuclear division starts, the centrosome divides into two organizing centres which migrate to each pole (along with the CENTRIOLES, if present) and the spindle develops between them.

centrosome

a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.
References in periodicals archive ?
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles.
2014) Dynamics of centrosome translocation and microtubule organization in neocortical neurons during distinct modes of polarization.
Inactivation of MAPK affects centrosome assembly, but not actin filament assembly, in mouse oocytes maturing in vitro.
Unlike animal cells, where microtubules are nucleated at discrete centriole containing centrosomes, plant cells produced a bewildering assortment of microtubule arrays in the absence of centrosomes.
Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members.
He discusses how experimental leukemia research started and developed, the progress of cancer concepts, early research, research on avian leukosis and sarcoma virus, mouse and rat viruses, studies on stem cells and cytokines, viral and chemical carcinogenesis, cell cycle control and centrosome, important oncogenes and suppressor genes and the related cell biology, skin carcinogenesis, DNA viruses, and the common pathway for retroviruses and chemicals.
he systematically investigated the question of which genes enable cancer cells to form centrosome clusters and, thus, to escape cell death.
Further studies suggest that the cellular infrared detector resides at the cell center within the centrosome, and contains centrioles that are light sensors.
Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair.
Centrosome hyperamplification in human cancer:chromosome instability induced by p53 mutation and/or Mdm2 overexpression.