centrosome


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centrosome

 [sen´tro-sōm]
a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.

cy·to·cen·trum

(sī'tō-sen'trŭm),
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
[cyto- + G. kentron, center]

centrosome

(sĕn′trə-sōm′)
n.
A small region of cytoplasm adjacent to the nucleus that contains the centrioles and serves to organize microtubules.

cen′tro·so′mic (-sō′mĭk) adj.

centrosome

(1) Uncertain; possibly the microtubule organising centre (MTOC). 
(2) The smallest hypothetical unit of life, the cytocentrum.

cy·to·cen·trum

(sī'tō-sen'trŭm)
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
Synonym(s): centrosome, microcentrum.
[cyto- + G. kentron, center]

centrosome

A small mass of CYTOPLASM, lying near the nucleus of a cell and consisting of a pair of centrioles, which divides into two parts before cell division. These migrate to the poles of the cell and the spindle develops between them.

centrosome

an area of cell CYTOPLASM found near the nucleus, whose function is thought to be the organization of nuclear division since it is capable of assembling and disassembling MICROTUBULES. When nuclear division starts, the centrosome divides into two organizing centres which migrate to each pole (along with the CENTRIOLES, if present) and the spindle develops between them.
References in periodicals archive ?
In the first stage, Aurora-A accumulates around centrosomes and suppresses actomyosin contractions locally in the surrounding cortex.
The researchers were able to show that Akna recruits and anchors microtubules at the centrosome.
Mitotic apparatus is comprised of some structures such as centrosomes, spindle poles, spindle microtubules, and chromosomes and intercellular bridge (11).
Ultrastructural studies show that animal cells usually contain one centrosome per cell except for the cells at M phase.
Euteneuer et al., "Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability," Traffic, vol.
Gynogenesis apparently functions to provide targeted oocytes with sperm-derived centrosomes which replace their developmentally eliminated original oocyte centrosomes [15].
Besides the mitochondria, of course centrosomes are another old improvement.
Kannan et al., "Identification of novel small molecule inhibitors of centrosome clustering in cancer cells," Oncotarget, vol.
Mulligan et al., "The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition," Blood, vol.
Feng, "Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome," The Journal of Neuroscience, vol.
The latter is the most abundant isoform expressed in most cells, which has been shown to be associated with the centrosome, suggesting a participation in cell cycle regulation [9].
BBS is a disease under the spectrum of 'ciliopathies' because molecular basis for this disease is that it affects the centrosome and affect the ciliary transport.