centromere

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Related to centromeric: kinetochore, telocentric chromosome

centromere

 [sen´tro-mēr]
the clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division. adj., adj centromer´ic.
 Position of the centromere in A, metacentric, B, submetacentric, C, acrocentric, and D, telocentric chromosomes. From Dorland's, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cen·tro·mere

(sen'trō-mēr),
1. The nonstaining primary constriction of a chromosome that is the point of attachment of the spindle fiber; provides the mechanism of chromosome movement during cell division; the centromere divides the chromosome into two arms, and its position is constant for a specific chromosome: near one end (acrocentric), near the center (metacentric), or between (submetacentric).
[centro- + G. meros, part]
Farlex Partner Medical Dictionary © Farlex 2012

centromere

(sĕn′trə-mîr′)
n.
The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

cen′tro·mer′ic (-mĕr′ĭk, -mîr′-) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

centromere

(1) An obsolete term for the neck of the sprematozoon. 
(2) Centromere; centromerus [NH3].
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

cen·tro·mere

(sen'trō-mēr)
The nonstaining primary constriction of a chromosome; the centromere divides the chromosome into two arms and its position is constant for a specific chromosome: near one end (acrocentric), near the center (metacentric), or between (submetacentric).
[centro- + G. meros, part]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

centromere

The constriction in a chromosome at which the two identical halves (chromatids) of the newly longitudinally-divided chromosome are joined, and at which the chromosome attaches to the spindle fibre during division (mitosis). The centromere contains no genes.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

centromere

a structure occurring at one point along the length of a CHROMOSOME, often visible under the light microscope as a bump or a constriction whose location can help to identify the chromosome. The centromere contains a complex system of fibres called the kinetochore which becomes duplicated when the chromosomes divide into CHROMATIDS. The kinetochore attaches to SPINDLE microtubules during nuclear division. Damaged chromosomes without centromeres (ACENTRIC CHROMOSOMES) fail to move normally during nuclear division.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Centromere

The centromere is the constricted region of a chromosome. It performs certain functions during cell division.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
NLA chromosomes displayed large telomeric signals on the centromeric regions of pairs 3 and 15 and on the sex chromosomes.
Heteromorphism occurs also in the X chromosomes of the female complement, which may differ both in centromeric position and size (Peshev 1983).
Metaphase spreads obtained from treated cells showed an array of structural chromosomal aberrations in the form of chromatid fragmentation, p-p arm Robertsonian fusions, premature centromeric separation, dicentrics, chromatid breaks, ring, end-to end fusion, endo-reduplication, markers, double minutes, tri- or quadric-radials.
The nearly identical survival of motor neuron 2, centromeric (SMN2) gene, a paralog of SMN1, also produces SMN protein, but at much lower concentrations.
The detection of the centromeric position and the measurement of arm lengths was found to be relatively difficult for some of the chromosomes and for this reason only the total length of the chromosomes are being reported here (Table 3).
Two separate, novel loci for complications were located outside the HLA region (Table 4, Figure 1(a)), one telomeric (42 cM) and one centromeric (64 cM) to the HLA region.
The inner kinetochore directly binds to the centromeric chromatin during the whole cell cycle.
The X chromosome had a centromeric C-positive area and the Y chromosome possessed a distinct dark pericentromeric C-positive band extending over the proxima third of the chromosome (Figure 3(1)).
simulans, near cytologicalband62), line [M.sub.S(82)] 6 (containing the centromeric region from D.
The LSI TCR alpha/ delta probe was a mixture of two probes that hybridize to the opposite sites of 14q11.2 with spectrum green on the telomeric side and spectrum orange on the centromeric side of the breakpoints.