central hypothyroidism


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central hypothyroidism

Endocrinology Hypothyroidism caused by pituitary or hypothalamic disease in the guise of tumors or vascular defects

central hypothyroidism

Hypothyroidism due to inadequate secretion of thyroid stimulating hormone (TSH) by the pituitary or of thyrotropin-releasing hormone (TRH) by the hypothalamus or by a malfunction in blood flow between the hypothalamus and the pituitary gland.
See also: hypothyroidism
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Hormonal investigations revealed hypopituitarism in the form of GH deficiency, central hypothyroidism, secondary adrenal insufficiency, secondary hypogonadism with hyperprolactinemia; the skull x- ray and standard sellar computed tomography (CT) were normal (9).
Other than the above reference, central hypothyroidism is not considered a cause of hyperprolactinemia.
Evaluation of the adequacy of levothyroxine replacement therapy in patients with central hypothyroidism.
If an organic lesion is excluded by CT/MRI in the child with central hypothyroidism, GH testing can be pursued, provided the hypothyroidism is first treated for 6 to 12 weeks.

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