central giant cell granuloma


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central giant cell granuloma

An osteodestructive lesion of uncertain pathogenesis, which most commonly occurs in the young female mandible, and is more lytic than peripheral giant cell granuloma.

Imaging
Radiolucent destructive lesion with faint trabeculation and loculation.
 
DiffDx
Giant cell bone tumour, PTH-induced “brown” tumour (hyperparathyroidism).
 
Management
Curettage.
References in periodicals archive ?
The surgical treatment of central giant cell granuloma of the mandible.
Radiographic features of central giant cell granuloma of the jaws in children.
Radiologic features of central giant cell granuloma of the jaws.
Central giant cell granuloma of the jaws: a clinical, radiologic and histopathologic study of 26 cases.
Provi- sional diagnosis of Ameloblastoma with differential diagnosis of central giant cell granuloma, odontogenic Fig 8: Shows diffusely scattered multinucleated giant keratocyst and ameloblastic fibroma was made and cells of varying size patient was advised for incisional biopsy.
5,6) Here we report a case of Central giant cell granuloma in mandible.
A clinical and histomorphologic comparison of central giant cell granuloma and the giant cell minor.
The unusual features of this case include the fact that the maxillary tumor was initially diagnosed as a benign central giant cell granuloma.
Central giant cell granulomas (arising from within the bonel are generally associated with hyperparathyroidism, whereas peripheral giant cell granulomas arising from or near the surface of the bone apparently are not associated with hyperparathyroidism (7); however it is advisable to test for hyperparathyroidism in the latter condition, if multiple lesions occur.

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