central dogma of molecular biology


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central dogma of molecular biology

The outdated principle which states that proteins are made from RNA, which in turn is made from DNA. Other permutations are found in nature; e.g., RNA viruses use a reverse transcriptase to make complementary DNA.
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Editor Witkowski has selected articles that present an insider's view of discoveries that are now seen as landmark achievements, and that relate to the central dogma of molecular biology, which is that DNA makes RNA makes protein, or, "once information has passed into protein it cannot get out again.
After an introduction to some of these key molecules and to the central dogma of molecular biology, we can begin to see the outlines of how such molecules can accomplish the tasks required of simple and then more complex life forms.
According to the central dogma of molecular biology, genes beget RNA molecules, and (usually) these beget proteins, which do most of the work in the cell.

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