In this section, we are going to explore another counterexample to the "Central dogma
"; the activity of transcription factors in assessing the state of metabolites in the cell, and so differentially affecting gene expression.
(2) The central dogma
in genetics is that individual genes (fixed sequences in the DNA) are copied to messenger RNA, which then exit the cell nucleus and attach to ribosomes.
The central dogma
is the agreed upon framework for understanding the transfer of information within and in between living organisms.
Taken together, they make up the "central dogma
" of biology:
A central dogma
of 20th-century education was that development and plasticity were reserved for children, and that the human brain changed little after childhood.
This is the first step in the so-called central dogma
of biology: DNA begets RNA begets protein.
After an introduction to some of these key molecules and to the central dogma
of molecular biology, we can begin to see the outlines of how such molecules can accomplish the tasks required of simple and then more complex life forms.
For here is a central dogma
of revisionism: we learn more from members of other religions than they do from us.
In his provocative paper, Unraveling the DNA Myth: The Spurious Foundation of Genetic Engineering, Barry Commoner, senior scientist at the Center for Biology of Natural Systems at Queens College, stated that most of this brave new science is predicated upon a central dogma
that is fundamentally and critically flawed.
Out of the structure of DNA emerged the so-called central dogma
of biology, from which all explanations of heredity and adaptation were supposed to flow.
The central dogma
of molecular biology--the proposition that information flows, in one direction, from DNA to RNA to protein--is hardly an archaic myth.
According to the central dogma
of molecular biology, genes beget RNA molecules, and (usually) these beget proteins, which do most of the work in the cell.