This cellular reprogramming
may be the key to cancer's ability to form new cell types, evolve drug resistance and metastasize to other locations in the body.
"This is an attractive possibility for cellular reprogramming
because multiple genes can be targeted at the same time.
Technology for cellular reprogramming
and its applications to the cancer epigenome
and Young Blood as Potential Antiageing Therapies?
As such, epigenetic regulation is critical for cellular reprogramming
as elaborated in other direct reprogramming processes .
Yasuhiro YAMADA "Development and Application of in vivo Cellular Reprogramming
Technology for Regulating Cancer Cell Fate"
Recently, scientists working at the Salk Institute for Biological Studies in California have found a way to reverse aging in mice through a process called cellular reprogramming
. They worked on mice that had been genetically engineered to grow old faster.
Now that we have confirmed that it's possible to reprogram wound cells to a very early stage of development we need to study if they can turn into more mature cell types and then study them in our 3D models to see if they will improve healing of chronic wounds," said Behzad Gerami-Naini, Ph.D., first author on the study in Cellular Reprogramming
and an assistant professor at Tufts University School of Dental Medicine.
(1) This report is the first-ever publication about successful cellular reprogramming
techniques that could generate an entire organ.
But the research offers a new approach to making stem cells and is a major first step in characterizing how cellular reprogramming
happens, says Wu.
He heads the laboratory of regenerative medicine at the Clinical Research Center for Pediatric Hematology, Oncology and Immunology where his research interests include Hutchinson-Gilford Syndrome, new methods of cellular reprogramming
, molecular mechanisms of skin and cartilage regeneration and personalized medicine in oncology.