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The term atypical cellular blue nevus has been applied to rare CBNs that show atypical histologic features and raise histologic differential diagnosis of malignant blue nevus.
Immunohistochemistry has been used in histologic differential diagnosis between cellular blue nevus, atypical cellular blue nevus, and malignant melanoma.
Key histologic features helpful in differentiating between cellular blue nevus, atypical cellular blue nevus, malignant blue nevus, and PEM are summarized in the Table.