cell-free protein synthesis

cell-free protein synthesis

The artificial production of proteins by the addition of MESSENGER RNA to a medium containing enzymes, amino acids, ribosomes, transfer RNA and cofactors.
References in periodicals archive ?
Sutro's proprietary and integrated cell-free protein synthesis and site-specific conjugation platform, XpressCF+, led to the discovery of STRO-001 and STRO-002, Sutro's first two internally-developed ADCs.
This is the first clinical trial on a product candidate created with cell-free protein synthesis.
Under the terms of the agreement, Sutro and Merck KGaA will collaborate to discover and develop multiple ADCs utilizing Sutro's cell-free protein synthesis platforms, Xpress CF and Xpress CF+.
Both firms will jointly discover and develop multiple antibody drug conjugates, antibodies linked to cytotoxic drugs for more targeted delivery, using Sutro's cell-free protein synthesis platforms Xpress CF and Xpress CF+.
coli, cell-free protein synthesis for analysis by NMR spectroscopy and structural proteomics of membrane proteins; biophysical and functional characterization of proteins, including a methods for protein characterization by mass spectrometry and thermal shift assay as well as multi-angle or static light scattering; structural characterization of proteins; and structural proteomics initiatives overviews.
Storch and Portner (2003) addressed the question of temperature-dependent costs of protein synthesis in cell-free protein synthesis extracts of gill tissue from European and Antarctic scallops and reported no difference between these two species.
Sawasaki, et al., A bilayer cell-free protein synthesis system for high-throughput screening of gene products, Febs Lett.
Roche Applied Science released the ProteoMaster Rapid Translation System for cell-free protein synthesis ...
STRO-001 and STRO-002 were developed using Sutro's proprietary cell-free protein synthesis and site-specific conjugation platforms, which facilitate precision design and rapid empirical optimization of protein conjugates to treat cancer and other diseases.
Cell-free protein synthesis; methods and protocols.
The research and development activities will leverage Sutro's proprietary cell-free protein synthesis and site-specific conjugation platforms, which facilitate precision design and rapid empirical optimisation of protein conjugates, to discover and develop best-in-class immune-modulating cytokine derivatives for both oncology and autoimmune indications.