cell receptors

cell receptors

; cell membrane receptors protein structures within cell membranes, activated by ligands (i.e. drugs, enzymes, biochemicals or hormones) to cause a cell membrane or intracellular effect; receptor numbers rise and fall in response to local needs and demand, e.g. receptor upregulation occurs when ligand-driven demand increases, and vice versa
References in periodicals archive ?
Immunocore's ImmTACs, a new class of drug with ultra-high affinity for intracellular cancer targets, are synthetic, soluble T cell receptors (TCRs) that recognise diseased cells containing disease specific targets.
It was found that two cell receptors specifically were responsible for the drug's anti-tumour effects.
The researchers also discovered that HIV-specific T cell receptors have to be matched to an individual in much the same way an organ is matched to a transplant patient.
The researchers will now begin making T cell receptors that target different parts of HIV and that could be used in more genetically matched individuals, he said.
A large family of NK cell receptors belongs to the C-type lectin super-family.
is a biopharmaceutical company specializing in high-quality antibodies that mimic the specificity of T Cell Receptors in the immune system.
Research shows a connection between nerve cell receptors implicated in inflammatory bowel disease and capsaicin's signal to the brain.
Just like cartographers can layer crime rate, smog, and rainfall onto a topographic map, scientists can layer variables like blood flow, abnormalities from disease or injury, and the distribution of cell receptors for important chemicals onto their image of the brain.
T cell receptors can be found on the surface of T cells, one of the major types of white blood cells involved in fighting diseases.
A fundamental problem in immunology is the recovery of B cell and T cell receptors in their native pairing configuration at the throughput necessary to truly understand the immune responses of patients or animals.
T Cell Receptors naturally recognise diseased cells and Immunocore's competitive advantage is its ability to engineer high affinity T Cell Receptors and link them to an antibody fragment which can activate the immune system to kill the targeted cancer or viral cells.
Amitabha Chattopadhyay and colleagues showed using lab tests, that long-term use of the drug caused significant changes in the structure and function of serotonin cell receptors.