cefuroxime


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Related to cefuroxime: Cefuroxime axetil, Cefixime

cefuroxime

 [sef″u-rok´sēm]
a semisynthetic, β-lactamase–resistant, second-generation cephalosporinantibiotic effective against a wide range of gram-positive and gram-negative bacteria; used as the sodium salt and the axetil ester.

cefuroxime

(sĕf′yə-rŏk′sēm′)
n.
A broad-spectrum cephalosporin antibiotic given orally and parenterally for respiratory, skin, and other infections.

cefuroxime

A second-generation CEPHALOSPORIN antibiotic active against staphylococci and some Gram-negative organisms. It must be given by injection. Brand names are Zinacef and Zinnat.

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.
References in periodicals archive ?
In conclusion, retinal toxicity may develop in complicated cases with the recommended cefuroxime concentration.
Intracameral cefuroxime and moxifloxacin used as endophthalmitis prophylaxis after cataract surgery: systematic review of effectiveness and cost-effectiveness.
The study shows that while the JAS price is among the lowest in the market for medicines like alprazolam and atorvastatin, there are cheaper branded medicines available in the market for a commonly prescribed antibiotic (cefuroxime axetil).
The activity of cefuroxime (p = 0.002), cefotaxime (p = 0.001), ceftazidime (p = 0.009), and cotrimoxazole (p = 0.001) was significantly higher in communityorigin than in hospital-origin isolates; however, amoxicillinclavulanic acid (p = 0.346), piperacillin-tazobactam (p = 0.176), imipenem (p = 0.144), gentamicin (p = 0.144), fosfomycin (p = 0.314), and nitrofurantoin (p = 0.164) showed no difference in activity between community- and hospitalorigin isolates.
All Streptococcal isolates recovered from uteri of mares were sensitive to Ampicillin, Cephalexin, Cefuroxime, Ceftriaxone, Chloramphenicol, Ciprofloxacin, Gentamicin and Tetracycline (100% each), but were relatively less susceptible to Cotrimoxazole (57.1%) and Penicillin (71.4%).
Once detected the sensitivity of these bacteria was checked for antibiotics like cefradine, cefuroxime, ceftriaxone, ciprofloxacin and amoxicillin.
The best available and logical choice which is also clinically proved could be a broad spectrum sec- ond generation cephalosporin.19 As for as bacterial spectrum of SSI is concern, Cefuroxime which is a broad spectrum second generation cephalosporin is one of the best fit antibiotic.20,21
Interactions of the essential oils (tea tree, lavender, cinnamon bark, marjoram and peppermint) when combined with ampicillin, carbenicillin, cefazolin, cefuroxime and ceftazidime indicate mainly 'no interaction'.
She took cefuroxime, 500 mg twice daily for 14 days, four weeks before the birth of baby and apparently she did not develop any side effects/toxicities from it.
were 100% susceptible to meropenem, piperacillin-tazobactam and cefoperazone-sulbactam followed by amikacin (83.33%) they were 100% resistant to cefuroxime, levofloxacin, chloramphenicol, cotrimoxazole, and tetracycline.
The antibiotic discs of amikacin (30 ug), aztreonam (30 ug), cefepime (30ug), cefixime (5 ug), cefotaxime (30 ug), ceftazidime (30 ug), cefuroxime (30 ug), ciprofloxacin (5 ug), co-amoxiclav (20/10 ug), co-trimoxazole (1.25/23.75 ug), gentamycin (10 ug), meropenem (10 ug), imepenem (10 ug), piperacillin-tazobactam (100/10 ug) and sulbactam-cefoperazone (75/30 ug) were placed on the Mueller-Hinton agar (Oxoid) plates and incubated at 37oC overnight.
All six antibiotic classes--azoles (Diflucan), macrolides (Zithromax), quinolones (Cipro), cotrimoxazole (Bactrim), penicillins (Ampicillin, Amoxicillin) and cephalosporins (Cefuroxime)--increased the risk, but to different degrees.