These include ciprofloxacin and pefloxacin , ofloxacin , lomefloxacin , tetracyclines , cefonicid
and other cephalosporins , and norfloxacin in quails .
(24) Geissler and coworkers found no significant difference in the rate of infection in minor gunshot wounds between patients who received 1 gm of intramuscular cefonicid
in the emergency room vs.
IV therapy consisted of 1 g cefonicid
(Monocid) every 12 hours, 1500 mg cefuroxime (Zinacef) every 8 hours, or 1 g amoxicillin/clavulanate every 8 hours.
In the other study, 1 g of cefonicid
was administered every 24 hours until the chest tube was removed, usually before 5 days (33).
In general, intermediate-spectrum cephalosporins, such as cefonicid
and cefoperazone, are also good for group B streptococci, staphylococci, coliforms, and anaerobic streptococci.