CAV2

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CAV2

A gene on chromosome 7q31.1 that encodes caveolin 2, the main scaffolding protein of the inner surface of caveolae (small invaginations of plasma membranes). Caveolin 2 is involved in essential cellular functions, including signal transduction, lipid metabolism, control of cell growth and apoptosis; it may function as a tumour suppressor.
References in periodicals archive ?
So far, 3 members of the caveolin family have been found in mammals: caveolin-1, caveolin-2 and caveolin-3.
Co-expression of caveolin-1 and caveolin-2 is widely distributed in various types of tissues and cells, such as epithelial cells, endothelial cells, adipocytes, fibroblasts, central nervous system and the placental tissues.
Caveolin-1 is a 21-kDa integral membrane protein and one of the major structural components of caveolae in most mammalian cells, along with caveolin-2 and caveolin-3.