caveolae


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caveola

 [ka″ve-o´lah] (pl. caveo´lae) (L.)
one of the minute pits or incuppings of the cell membrane formed during pinocytosis.

caveola

(kăv-ē-ō′lă) plural.caveolae
A small pit or depression formed on the cell surface during pinocytosis.
References in periodicals archive ?
Caveolae formations start with expression of integral membrane proteins caveolin-1 or caveolin -2 in ER followed by their oligomerization (7-14 molecules of caveolin) and COPII-dependent transportation to the Golgi.
Through cholesterol depletion, statins cause caveolae collapse in adipocytes inducing proteasomal degradation of cavin2 and redistribution of cavin-1 to the cytosol [89].
Cav-1 protein is a component of caveolae invaginated microdomains of the plasma membrane that is present in most mammalian cells [5].
In addition, a report has demonstrated a vesicular structure due to the retraction of plasma membrane in cells, and this nest vesicle is also named as Caveolae. CAV is the marker protein of Caveolae [22].
Other authors reported that extracellular [alpha]-synuclein uptake by microglial cells is mediated by the GM1 ganglioside as well as by hitherto-unknown protein receptors in clathrin-, caveolae, and dynamin-independent, but lipid raft-dependent processes [90].
The pores on tumor vasculature include caveolae, vesiculo-vacuolar organelles, and fenestrations that are on the order of 10-20 nm along with larger but sporadic interendothelial cell gaps, which are significantly larger than 200nm in diameter [16-20].
Toborek, "Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells," Biochemical and Biophysical Research Communications, vol.
Lutz, "Angiotensin II-induces activation of RhoA via an AT(1)R-, G(q/11)- and p63RhoGEF-dependent pathway in caveolae of neonatal cardiac fibroblasts," Naunyn-Schmiedebergs Archives of Pharmacology, vol.
Internalization via caveolae is not a constitutive process but only occurs upon cell stimulation.
(21.) Song JH, Kim M, Park SW, Chen SW, Pitson SM, Lee HT Isoflurane via TGF-betal release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules.
Caveolin-1 is an iconic structural molecule of Caveolae. Because of its pivotal role in the process of cell proliferation, apoptosis and other related signaling pathways of human tumors, caveolin-1 has been extensively studied.