cathepsin


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Related to cathepsin: Cathepsin C

cathepsin

 [kah-thep´sin]
an endopeptidase found in most cells, which takes part in cell autolysis and self-digestion of tissues.

ca·thep·sin

(kă-thep'sin),
One of a number of intracellular proteinases and peptidases (all endopeptidases) of animal tissues of varying specificities.

cathepsin

(kə-thĕp′sĭn)
n.
Any of various enzymes found in animal tissue that catalyze the hydrolysis of proteins into smaller proteins.

cathepsin

Any ENZYME that acts to split the interior PEPTIDE bonds of a protein, causing its decomposition.

cathepsin

or

kathepsin

the intracellular, proteolytic enzymes that bring about AUTOLYSIS.
References in periodicals archive ?
Purification and partial characterization of ostrich skeletal muscle cathepsin D and its activity during meat maturation.
Also, there was a strong trend in protease inhibition upon brine incorporation, although there were not significant differences in cathepsin L activity at the ultimate pH between treatments.
Murohara, "Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication," Circulation, vol.
Mellins, "Cathepsin G: roles in antigen presentation and beyond," Molecular Immunology, vol.
Murohara, "Cysteine protease cathepsins in atherosclerosis-based vascular disease and its complications," Hypertension, vol.
A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme activation and NK cell cytolytic activity.
Conclusion: The present study reveals significant results for the patients diagnosed with invasive ductal carcinoma through breast biopsy especially before mastectomy in terms of increased number of metastatic axillary lymph nodes and extranodal tumor invasion by immunohistochemical Cathepsin D stain without any additional invasive intervention.
Dice, "Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor," The EMBO Journal, vol.
Hsueh et al., "Imbalanced Rab3d versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjogren's syndrome," American Journal of Physiology--Cell Physiology, vol.
These hydrolases, which include the cathepsin family of proteases, are responsible for degradation, recycling, and disposal of cellular macromolecules [1].
The activities of cathepsin K and matrix metalloproteinases (MMPs) in the collected media were measured using SensiZyme cathepsin K assay kit (Sigma-Aldrich) and gelatin zymography, respectively, and the resorbed pits on the plate were observed under light microscope (x100 magnification), as previously described [16, 17].