cathepsin


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Related to cathepsin: Cathepsin C

cathepsin

 [kah-thep´sin]
an endopeptidase found in most cells, which takes part in cell autolysis and self-digestion of tissues.

ca·thep·sin

(kă-thep'sin),
One of a number of intracellular proteinases and peptidases (all endopeptidases) of animal tissues of varying specificities.

cathepsin

/ca·thep·sin/ (kah-thep´sin) one of a number of enzymes each of which catalyzes the hydrolytic cleavage of specific peptide bonds.

cathepsin

(kə-thĕp′sĭn)
n.
Any of various enzymes found in animal tissue that catalyze the hydrolysis of proteins into smaller proteins.

cathepsin

Any ENZYME that acts to split the interior PEPTIDE bonds of a protein, causing its decomposition.

cathepsin

or

kathepsin

the intracellular, proteolytic enzymes that bring about AUTOLYSIS.

cathepsin

a proteinase found in most cells, which takes part in cell autolysis and self-digestion of tissues.

cathepsin D
an acid hydrolase isolated from cartilage which plays a part in the endogenous degradation of proteoglycans in degenerative diseases of joints.
References in periodicals archive ?
High bone mineral density in pycnodysostotic patients with a novel mutation in the propeptide of cathepsin K.
A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme activation and NK cell cytolytic activity.
Ultraviolet A-induced cathepsin K expression is mediated via MAPK/AP-1 pathway in human dermal fibroblasts.
Protein hydrolysis by Colorado potato beetle, leptinotarsa decemlineata, digestive proteases: the catalytic role of cathepsin D.
Metalloproteases and cathepsin extracts gave higher specific activities (TABLE I).
Moreover, sanguiin H-6 downregulated osteoclast marker proteins, including NFATc1, c-Src, and cathepsin K, inhibited RANKL-induced nuclear translocation of NFATc1, phosphorylated-cFos, and NF-[kappa]B, as well as TNF-[alpha]-induced osteoclastogenesis in vivo.
Nobody has shown before cathepsin B's effect on spatial learning," says van Praag, who collaborated on the study with Emrah Duzel and colleagues at Otto-von-Guericke University and the German Center for Neurodegenerative Diseases.
Cysteine proteinase 1 (CP1), a cathepsin L-like enzyme expressed in the Drosophila melanogaster haemocyte cell line mbn-2.
Plasma cathepsin S and cystatin C levels were compared among the groups by analysis of variance and the Scheffe test.
Cathepsin K is a lysosomal cysteine protease belonging to the papain superfamily and it has been cloned in 1999.
Cathepsin B activity assay kit and apoptosis assay kit were from BioVision (USA) and KenGEN BioTECH (Nanjing, China), respectively.