cataplexy


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cataplexy

 [kat´ah-plek″se]
a condition, often associated with narcolepsy; marked by abrupt attacks of muscular weakness and hypotonia triggered by an emotional stimulus, such as mirth, anger, or fear. adj., adj cataplec´tic.

cat·a·plex·y

(kat'ă-plek'sē),
A transient attack of extreme generalized weakness, often precipitated by an emotional response, such as surprise, fear, or anger; one component of the narcolepsy quadrad.
[cata- + G. plēxis, a blow, stroke]

cataplexy

(kăt′ə-plĕk′sē)
n. pl. cataplex·ies
A sudden loss of muscle tone and strength, usually caused by an extreme emotional stimulus.

cat′a·plec′tic (-plĕk′tĭk) adj.
A rare—1:2,000—condition characterised by recurrent episodes of abrupt decrease/loss of muscle tone either limited to muscle groups, or generalized, leading to muscle weakness, paralysis or postural collapse; cataplexy in an awake person is pathognomonic of narcolepsy, and is triggered by emotional stimuli or stress, which may cause knee-buckling; cataplectic attacks are dangerous for machinists, house painters, construction workers
Precipitating factors Outburst of emotion, strenuous physical exercise, flashes of light. It may present as a side effect of SSRI discontinuation syndrome
Diagnosis Flat EMG potentials, loss of tendon reflexes during an attack, eye movements similar to those of REM sleep, REM sleep pattern immediately on falling asleep
Management Imipramine, protripyline, IMAOs

cataplexy

Neurology An abrupt ↓/loss of muscle tone either limited to muscle groups, or generalized, leading to muscle weakness, paralysis or postural collapse; cataplexy in an awake person is pathognomonic of narcolepsy, and is triggered by emotional stimuli or stress, which may cause knee-buckling; cataplectic attacks are dangerous for machinists, house painters, construction workers Management Imipramine, protripyline, IMAOs. See Narcolepsy.

cat·a·plex·y

(kat'ă-plek-sē)
A transient attack of extreme generalized muscular weakness, often precipitated by an emotional state such as laughing, surprise, fear, or anger.
[cata- + G. plēxis, a blow, stroke]

cataplexy

The momentary paralysis, or weakness of the limbs, that sometimes affects people surprised by a strong emotion such as, anger, fear, jealousy, happiness or hilarity.

cataplexy

a human nervous condition in which individuals suddenly collapse to the ground without loss of consciousness. It can be induced by strong emotion.

Cataplexy

A symptom of narcolepsy in which there is a sudden episode of muscle weakness triggered by emotions. The muscle weakness may cause the person's knees to buckle, or the head to drop. In severe cases, the patient may become paralyzed for a few seconds to minutes.
References in periodicals archive ?
Hypocretin is a recently-defined neuropeptide and its levels in CSF have been found low in approximately 90% of patients with idiopathic narcolepsy and cataplexy (8).
Can boxer cross Poppy help Emily who suffers from narcolepsy and cataplexy?
It wasn't until 2012 that she discovered she also has cataplexy, which has no cure.
Narcolepsy causes profound sleepiness, vivid dreams, sleep paralysis, hallucinations as you drift into our out of sleep, and cataplexy, the sudden loss of muscle strength, usually precipitated by strong emotion.
Excessive daytime sleepiness, as presented, in this case, affected 32% of the patients, sometimes with narcolepsy cataplexy. [sup][1] After receiving oncological treatment and immunotherapy, including steroids, IVIg and plasma exchange, some patients have neurological improvement.
| Cataplexy - temporary loss of muscle control, often in response to emotions such as laughter and anger.
She says the debilitating condition - which causes her to suer sleep attacks, night terrors and cataplexy where she collapses due to muscle weakness - has stopped her living a normal life.
Thomas started falling, as well, a part of the disease called cataplexy.
Anita Wainwright, a mother of four from Birmingham, suffers from a rare medical condition, cataplexy, which causes her to have seizure and collapse every time she has heightened emotions.
[2] About 10% of individuals with narcolepsy have the four core symptoms of narcolepsy: paroxysmal sleep, cataplexy, hypnagogic hallucination, and sleep paralysis.