Glucose and related sugars repress the transcription of genes required to utilize certain carbon sources such as xylan or cellulose by carbon catabolite repression (CCR) .
In this study mutagenesis approach was used to reduce the catabolite repression effects of simple sugar glucose.
These results might be attributed to the fact that the presence of readily available substrates has been noted to influence the biosynthesis of many extracellular enzymes via catabolite repression
mechanism (Vijayaraghavan et al.
2001) reported carbon catabolite repression of the enzyme, as FFH production was checked by the presence of monosaccharides like glucose and fructose in the medium.
Afterwards, enzyme activity declined due to decrease in nutrients availability in the medium, or carbon catabolite repression, as the expression in yeast is checked by the presence of monosaccharides like glucose and fructose as reported by Samia (2008).
These results appear to support catabolite repression
by glucose and sorbitol with prodigiosin production.
Effects of anaerobic regulatory mutations and catabolite repression on regulation of hydrogen metabolism and hydrogenase isoenzyme composition in Salmonella tyhimurium.
A multiplicity of potential carbon catabolite repression mechanisms in prokaryotic and eukaryotic microorganisms.
The inhibition of this synthesis is called catabolite repression
(CR) and the abundance of glucose, glycerol or other readily found fermentable carbon sources inhibit this enzyme synthesis .
The biosynthesis of [alpha]-amylase in most species of the genus Bacillus is repressed by readily metabolizable substrates, especially glucose, by a mechanism of catabolite repression
However, some catabolic genes like amyE and XynA are regulated by carbon catabolite repression
instead of substrate induction.
Decrease in biomass with high xylose concentration may be due to catabolite repression
during aerobic metabolism.