xylosoxidans colonies failed to grow on aniline agar plates which were possibly due to fact that genes involved in aniline catabolic pathway
were plasmid encoded.
Hereditary tyrosinemia Type I (HTI, OMIM 276700) is a rare inborn error of tyrosine metabolism due to deficiency of the enzyme fumarylacetoacetate hydrolase (FAH), the last enzyme in the tyrosine catabolic pathway
(1) (Figure 1).
This process requires both sphingolipids as intermediates of the de novo sphingolipid biosynthesis pathway and sphingolipids as intermediates of the SM catabolic pathway
In contrast, dietary patterns that are denser in fiber and are polyphenol rich, as would be characteristic of the Mediterranean Diet, promote a differing catabolic pathway
. The catabolic pathway
of choice with this dietary pattern is fermentation, otherwise known as saccharolytic.
Second, several genes with gene coding for uridine diphosphate-glucuronosyltransferase are involved in the regulation of serum bilirubin levels by the heme catabolic pathway
. (28) However, genomic DNA from patients with TA was not available in the current study.
Caption: Figure 8: The differential expression level of key enzyme genes involved in ABA biosynthetic and catabolic pathway
under drought stress.
The catabolic pathway
also depletes intracellular concentrations of spermidine and spermine, which are free radical scavengers (Figure 2).
increased too, serum S.A XDH showed a significant negative correlation with XO/XDH ratio figure (1,D), XO/XDH ratio showed a significant positive correlation with uric acid and Mo figure (1,E& F) we expect the positive correlation with uric acid may be due to the parallel increasing in XO activity observed in cholelithiasis patients reflect the fact that the catabolic pathway
is increased, and this supports our results in Table (1), Mo element is a component of enzymes (XO, XDH) we suggest that the reason for positive correlation with Mo.
Hereditary Tyrosinemia Type 1 (TT1) is an autosomal recessive disorder that is characterized by the deficiency of the FAH enzyme in the tyrosine catabolic pathway
, resulting in the elevation of tyrosine and its byproducts in the blood, CSF, and tissues.
Since the catabolic pathway
of L-hydroxyproline is not included in the models, we did not perform the growth simulation on lhydroxyproline.
Alkaptonuria is a rare metabolic disorder in the phenylalanine and tyrosine catabolic pathway
which is characterized by the excessive excretion of homogentisic acid in the urine, ochronosis, and debilitating arthritis of the spine and large joints.