castanospermine


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castanospermine

pyrrolizidine alkaloid in the ripe seeds of Castanosperma australe. Powerful inhibitor of mononuclear cell beta-glucosidase which is however not the cause of the seeds' toxicity.
References in periodicals archive ?
The dry CAS extract powder mainly contains alkaloids castanospermine (RT=10.
Docking results showed that all the three isoforms of castanospermine has been showing hydrogen bonding with catalytic residues of DPP-4.
0 Table 3 GOLD score and predicted binding affinity of Castanospermine isoforms compared to Berberin.
In the latest research, castanospermine and dNM "completely inhibited' giant-cell formation for 6 hours after the drugs were mixed with cells, and then greatly decreased it for several days after the mixing, say the scientists.
Folks, who does similar experiments with other enzyme-blocking agents, told SCIENCE NEWS that the low toxicity of dNM and castanospermine also is important.