caspase


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Related to caspase: Caspase 3, Caspase 9

caspase

(kas'pās),
An enzyme implicated in apoptosis, which cleaves proteins after asparatic acid. (Thus, c aspase.)

caspase

A protein that regulates programmed cellular death (apoptosis).
References in periodicals archive ?
Representative western blot graphs showing the effects of tumor necrosis factor-[alpha] (TNF- [alpha]) on the protein expression levels of Specific marker proteins receptor interacting protein kinase (RIPK3) (A), mixed lineage kinase domain-like protein (MLKL) and p-MLKL (B), caspase 3 and cleaved caspase 3 (C), and [beta]-actin in MC3T3-E1 cells.
They consist of three components: sensors, ASC, and caspases. There are subvariants of sensors and caspases, such as NLRP1, NLRP3, caspase-1, and caspase-4, marking variable inflammasomes with different biological functions.
Apoptotic protein expression and activation of caspases is changed following cholinergic denervation and hippocampal sympathetic in growth in rat hippocampus.
Caspase-3 is one of the effector caspases that can be measured for the number of apoptosis in cancer cells.
Pawlick et al., "The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice," Diabetes, vol.
They function as an activating scaffold for inflammatory caspases that play an essential role in the maturation and secretion of proinflammatory cytokines as well as in pyroptosis, an inflammatory death of infected cells [26, 27].
(ERINLG-4) induces apoptosis in human lung cancer A549 cells through p53 and cytochrome c release caspase dependant pathway," Chemico-Biological Interactions, vol.
Furthermore, weak brown-colored MCF7 cells were observed by tiliroside 50 [micro]g/ml from the expression of Caspase 8.
This kit detect apoptosis by assaying the increase in caspase 3 protease activity.
The caspases as a novel group of 10 cysteine proteases are the major enzymes involved in the process of apoptosis [21] and are responsible for execution of apoptosis [22].

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