The typical histopathologic feature is the presence of granulomas with central caseous
necrosis; the areas of necrosis are surrounded by epithelioid cells and by Langhans' giant cells that feature multiple nuclei arranged in a horseshoe-shaped pattern.
Presence of sheets of epithelioid cells with lymphocytes and plasma cells with or without multinucleated giant cells were diagnosed as granulomatous lymphadenitis, and eosinophilic granular material containing inflammatory cells and necrotic cell debris was defined as caseous
On clinical examination, all dogs having aural hematoma except one showed apparently healthy ear canal, one dog with bilateral aural hematoma showed caseous
purulent discharge with ceruminoliths.
Fine-needle aspiration cytology (FNAC) is a simple, quicker, reliable, minimally invasive, and relatively cheap diagnostic modality with minimal risk of complications. The efficacy of FNAC to diagnose TB lymphadenitis is directly proportional to presence of purulent material in sample. AFB are commonly seen in purulent samples, which may not contain granuloma, caseous
necrosis, or epithelioid cells.
The bacteria grew from [greater than or equal to] 1 delimited pseudotuberculosis-like caseous
abscess, arranged in concentric layers and ranging from 0.1 to 10 cm in diameter (Figure 2).
Histopathologic examination of the involved middle ear and mastoid mucosa will show three types of changes: miliary, granulomatous, and caseous
.(1) The miliary type is associated with superficial infection, the granulomatous type with superficial bony involvement, and the caseous
type with massive necrosis and sequestration.(4)
The first was characterized by the presence of focal/multifocal granulomatous inflammation, consisting of a well-defined focus of inflammatory cells, sometimes surrounded by a ring of fibrous tissue, with or without central caseous
It has been observed that in tuberculoid leprosy, T cells breach the perineurium, and destruction of Schwann cells and axons may be evident, resulting in fibrosis of the epineurium, replacement of the endoneurium with epitheliod granulomas, and occasionally caseous
Orf and Caseous
lymphadenitis have been dealt with previously in this column and so will not be discussed here.
In addition to this all the fifteen hilar and para-aortic lymph nodes showed caseating granulomas with Langhans giant cells and extensive areas of caseous
necrosis without any evidence of tumour deposits.
On cut section, the masses contained caseous
and necrotic discharge from the epididymis was present.