case-control study

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Related to case-control study: cross-sectional study, Cohort study

case-control study

a nonexperimental research design using an epidemiological approach in which previous cases of the condition are used in lieu of new information gathered from a randomized population. A group of patients with a particular disease or disorder, such as myocardial infarction, is compared with a control group of persons who have not had that medical problem. The two groups, matched for age, sex, and other personal data, are examined to determine which possible factor (e.g., cigarette smoking, coffee drinking) may account for the increased disease incidence in the case group. See also retrospective study.

case-con·trol study

(kās-kŏn-trōl stŭdē)
Epidemiologic method that begins by identifying people with a disease or condition of interest and compares their past history of exposure to identified or suspected risk factors with the past history of similar exposures among those who resemble the cases but do not have the disease or condition of interest.


in epidemiology, an animal which has the specified disease or condition which is under investigation.

case abstract
a structured summary of a case report suitable for computer entry; permits machine sorting and retrieval and leads an investigator to the original paper records on which detailed descriptions must be based.
case-control sampling
selection of cases as a sample to use in a case-control study (below).
case-control study
a retrospective, analytical, epidemiological study. A group of pre-existing cases of the disease are matched with a selected group of control animals that do not have the disease so that the presence or otherwise of an hypothesized disease determinant can be ascertained in both groups.
case fatality rate
the proportion of cases with a specified condition which die within a specified time.
case finding
the strategy of surveying a population to find the sick animals that are the foci of infection; an essential early step in the eradication of any disease.
case history
the collected data concerning an individual, contact and related animals, environment and management procedures, including any past medical history and any other information that may be useful in analyzing and diagnosing the case or for instructional or research purposes.
index case
the first case recorded in an outbreak.
case management
care of a sick animal including specific and supportive medication, surgical intervention, housing, bedding, nutrition, restraint, collection of specimens for submission to laboratory or stall-side tests.
case population
the group of animals in the total population which are sick or infected, as distinct from the control population, which are not sick or infected.
case recording
entry in records of the clinical findings of individual sick animals. May be structured or unstructured, paper or machine, with or without the accounting record for the case.
References in periodicals archive ?
A case-control study to investigate an association between adverse pregnancy outcome and periodontal disease.
The National Cancer Institute recently approved funding for a new population-based case-control study focusing on second primary cancers.
Another case-control study of 300 cases (239 males 61 females) and 300 controls was conducted in Germany17 from 1989 to 1992.
Risk factors for indigenous campylobacter infection: a Swedish case-control study.
Even in the smaller case-control study that found a suggestion of elevated risk, the authors think that, at most, 3% of cases of atrial fibrillation might be attributable to oral alendronate.
The effect of residence in the same census tract as a dump site was not, however, detected in the case-control study.
For example, if having breast cancer biases what a woman eats or says she eats, that would distort the results of a case-control study.
based National Institute of Child Health and Human Development (NICHD) and Centers for Disease Control in Atlanta tested the pill-cancer connection in a case-control study of more than 4,000 women aged 20 to 45.
Increased adenocarcinoma of the lung was observed among users of coal or anthracite as cooking fuel in a case-control study in Taiwan (n = 1,332) (Lee CH et al.
Although those estimates are unstable because of the low number of events, a case-control study of nearly 10,700 infants with a major congenital abnormality and more than 21,500 healthy controls showed no significant association between lithium and congenital abnormalities.
We conducted an age-stratified case-control study with 753 sCJD patients and 210 controls and a study of patients who underwent neurosurgical or ophthalmic surgical procedures at the same hospital.