GDF.af.5

(redirected from cartilage-derived morphogenetic protein-1)

GDF.af.5

A gene on chromosome 20q11.2 that encodes a member of the bone morphogenetic protein (BMP) family, which regulates cell growth and differentiation in both embryonic and adult bone and cartilage.

Molecular pathology
GDF5 mutations are associated acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type.
References in periodicals archive ?
1114insGAGT) in gene coding cartilage-derived morphogenetic protein-1 (CDMP1).
A novel insertion mutation in the cartilage-derived morphogenetic protein-1 (CDMP1) gene underlies Grebetype chondrodysplasia in a consanguineous Pakistani family.