Cartilage-derived morphogenetic protein-1 | definition of cartilage-derived morphogenetic protein-1 by Medical dictionary
GDF.af.5 (redirected from cartilage-derived morphogenetic protein-1)
GDF.af.5 A gene on chromosome 20q11.2 that encodes a member of the bone morphogenetic protein (BMP) family, which regulates cell growth and differentiation in both embryonic and adult bone and cartilage.
GDF5 mutations are associated acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type.
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References in periodicals archive
Genetic analysis revealed four base pair insertion mutation (c.1114insGAGT) in gene coding cartilage-derived morphogenetic protein-1 (CDMP1).
A novel insertion mutation in the cartilage-derived morphogenetic protein-1 (CDMP1) gene underlies Grebetype chondrodysplasia in a consanguineous Pakistani family.