If the work can be replicated in animals and then developed into a clinical therapy, the engineered cells or cartilage grown from stem cells would respond to inflammation by releasing a biologic drug -- the TNF-alpha inhibitor -- that would protect the synthetic cartilage cells
that Guilak's team created and the natural cartilage cells
in specific joints.
hWJMSCs also express cell growth factors, chemokines, and cytokines at levels similar to those of cartilage cells
The method simulated the effect of articular cartilage composition, structure and various loadings on the volume, shape and mechanical responses of cartilage cells
But cartilage cells
in your nose can grow very quickly - making them invaluable to doctors.
The remarkable thing about stem cells is the fact that when you inject them into a specific area of the body, they know what kinds of cells the body needs -- for example, meniscus cells or cartilage cells
. It is a very exciting time in the field of regenerative medicine.
The nonviable cells exhibited degenerative changes in the cartilaginous matrix and empty cartilage lacunae from which the cartilage cells
The new procedure removes cartilage cells
surgically from the damaged knee and mixes them with specially selected donor stem cells.
Stockwell, Biology of Cartilage Cells
, Cambridge University Press, Cambridge, UK, 1979.
The team used a 3D printer to create a titanium mesh scaffold for the ear, which was then seeded with sheep cartilage cells
. The cells grew across the mesh over a period of about three months, creating an ear that can be tailored to mimic the recipient's natural aural appendages--a vast improvement over the current laborious process in which a plastic surgeon carves a rough ear out of cartilage harvested from the patient's own ribs.
A team of researchers at Kyoto University has succeed in creating cells with the characteristics of cartilage cells
using human skin cells, using a method faster than producing them from stem cells, according to a study published Thursday in the U.S.
Ian Clark, professor of musculoskeletal biology at the Norwich university, said: "We have shown that this works in the three laboratory models we have tried, in cartilage cells
, tissue and mice.
But after having cartilage cells
applied to the damaged area during surgery, he was chosen to play for Hungary in a 15-16 defeat to Cyprus in the European Nations Cup.